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NCT07021079: NEUROVIB-ULLS
Muscle Vibration as a Countermeasure Against Hypoactivity-induced
NA trial testing Focal muscle vibration in Vibration Therapy in 42 participants. Currently enrolling.
1 June 2027
Quick facts
| Lead sponsor | Centre Hospitalier Universitaire de Saint Etienne |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 42 |
| Start date | 16 June 2025 |
| Primary completion | 1 June 2027 |
| Estimated completion | 31 August 2027 |
| Sites | 1 location across France |
Drugs / interventions tested
- Focal muscle vibration
- NO Focal muscle vibration
Conditions studied
- Vibration Therapy — all drugs for Vibration Therapy →
- Healthy Volunteer Study — all drugs for Healthy Volunteer Study →
- Hypoactivity — all drugs for Hypoactivity →
Sponsor
Centre Hospitalier Universitaire de Saint Etienne
Who can join
Adults 19 to 45, any sex, with Vibration Therapy or Healthy Volunteer Study. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Muscle deconditioning, characterized by a loss of muscle mass and strength, is a frequent consequence of prolonged lower limb unloading. Beyond muscle mass loss, reduced neural drive contributes significantly to strength decline, highlighting the need for interventions targeting neuromuscular function during immobilization. Focal muscle vibration (FMV) has shown promise in modulating neuromuscular excitability by activating muscle spindle afferents and inducing cortical adaptations. Chronic use of FMV has been associated with significant strength gains and improved neural command. This makes FMV an effective rehabilitation tool. Its simplicity and non-invasiveness further make it a practical countermeasure.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07021079
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Focal muscle vibration
Trials testing the same drug.
- NCT06893653 — Focal Muscle Vibration and tDCS on Motor Recovery in Stroke · NA · recruiting
- NCT05751135 — Impact of Focal Muscle Vibration on Bio-psychosocial Outcomes in Cerebral Palsy · NA · completed
- NCT05322746 — Focal Vibrations and Neuropathic Pain in Diabetic Peripheral Neuropathy · NA · completed
Other recruiting trials for Vibration Therapy
Currently open trials in the same condition.
- NCT06413524 — The Effects of Different Vibration Exercises on COPD Patients · NA · recruiting
Other Centre Hospitalier Universitaire de Saint Etienne trials
Trials by the same sponsor.
- NCT07326579 — Effects of a Sleep Education Program on the Health Status of Healthcare Workers Working 12-hour Alternating Day-night Sh · NA · not yet recruiting
- NCT07504003 — Influence of Training Session Duration on Improvements in Physiological Resilience to Exercise · NA · recruiting
- NCT07483710 — Association Between Muscle L3 CT Scan Muscle Derived Parameters of Muscle Function Upon Intensive Care Unit Admission an · NA · not yet recruiting
- NCT06845176 — Combining Motor Imagery and Tendon Vibration on the Effectiveness of Motor Imagery · NA · recruiting
- NCT07344298 — Less is Better? Effectiveness of a Short Local Vibration Protocol on Neuromuscular Function · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07021079 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire de Saint Etienne
- Last refreshed: 26 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07021079.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing