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NCT07017296
Microencapsulated Pomegranate Juice as Anti-Hypertensive
NA trial testing Placebo in Clinical Trial in 20 participants. Completed in 1 May 2025.
31 December 2024
Quick facts
| Lead sponsor | Universidad Autónoma del Estado de Hidalgo |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 15 August 2024 |
| Primary completion | 31 December 2024 |
| Estimated completion | 1 May 2025 |
| Sites | 1 location across Mexico |
Drugs / interventions tested
- Placebo
- Positive control — full drug profile →
- Active comparator — full drug profile →
- Control
Conditions studied
- Clinical Trial — all drugs for Clinical Trial →
Sponsor
Universidad Autónoma del Estado de Hidalgo
Who can join
Adults 45 to 65, female only, with Clinical Trial. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Introduction: Hypertension is a significant risk factor for cardiovascular disease (CVD). Pomegranate is a fruit rich in polyphenols that exerts an antihypertensive effect. Objective: The present work evaluated microencapsulated pomegranate juice (MPJ) as an anti-hypertensive in patients with mild hypertension. Materials and Methods: The content of phenols, flavonoids, anthocyanins, and antioxidant activity in fresh pomegranate juice (FPJ) and MPJ was determined. Subsequently, the postprandial anti-hypertensive effect was evaluated in recruited participants who consumed approximately 480 kcal breakfast. Four experimental groups with five participants each were evaluated: FPJ, 150 mL fresh juice; MPJ, 20 g microencapsulated pomegranate juice; the participant's usual drug (AH); and 150 mL water (W) with breakfast. Each participant's blood pressure (BP) was measured before and after breakfast at 30, 60, 90, and 120-min. Changes in BP values were evaluated as a function of time using generalized linear models.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Postprandial Antihypertensive Evaluation of Microencapsulated Pomegranate Juice in Women With Mild Hypertension: A Randomized Pilot Study.
Betanzos-Cabrera G, Cabrera-García P, Fabella-Illescas HE, Valle-Mondragón LD, et al · · 2026 · PMID 41938572 · DOI 10.1155/ijhy/7665540
Verify or expand the search:
- PubMed search for NCT07017296
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07017296 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidad Autónoma del Estado de Hidalgo
- Last refreshed: 12 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07017296.
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