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NCT06954779
Arginine Plaque Metabolism Pilot Clinical Study
Phase 3 trial testing Colgate Cavity Protection in Plaque, Dental in 20 participants. Completed in 20 September 2024.
20 September 2024
Quick facts
| Lead sponsor | Colgate Palmolive |
|---|---|
| Phase | Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | sequential |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 24 July 2024 |
| Primary completion | 20 September 2024 |
| Estimated completion | 20 September 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Colgate Cavity Protection — full drug profile →
- TOM's Superior Sensitivity Relief Toothpaste — full drug profile →
Conditions studied
- Plaque, Dental — all drugs for Plaque, Dental →
Sponsor
Colgate Palmolive — full company profile →
Who can join
Adults 18 to 70, any sex, with Plaque, Dental. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Proof of concept clinical study to measure plaque metabolism and the prebiotic efficacy of arginine-containing toothpaste.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06954779
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Colgate Cavity Protection
Trials testing the same drug.
- NCT06733285 — Clinical Study to Investigate the Ability of a Stannous Fluoride Toothpaste to Protect From Dentine Hypersensitivity · NA · completed
- NCT06563518 — Clinical Study of Toothpaste Containing Zinc Lactate as Compared to Colgate Cavity Protection Toothpaste. · Phase 2 · completed
- NCT04050722 — A Clinical Study Investigating the Efficacy of a Stannous Fluoride Dentifrice in Improving Gingival Health After Twice D · Phase 4 · completed
- NCT05138978 — Metagenomic and Metatranscriptomic Analysis of Clinical Plaque Samples · Phase 2 · completed
Other recruiting trials for Plaque, Dental
Currently open trials in the same condition.
- NCT06017817 — Antibacterial Photodynamic Therapy in the Management of Peri-implantitis · NA · recruiting
- NCT06453005 — Comparative Evaluation of SMART Hall Technique Vs. Conventional SS Crown in Primary Molars: a Randomized Clinical Trial · NA · recruiting
- NCT05965076 — Analysis of the Effectiveness of the Use of Glycine Powder and Angled Implant Brush in Oral Hygiene Maintenance in Patie · NA · recruiting
- NCT05384132 — Novel Dental Gel as an Adjunct to Scaling and Root Planing · NA · recruiting
Other Colgate Palmolive trials
Trials by the same sponsor.
- NCT07398846 — Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reduci · Phase 3 · recruiting
- NCT07276672 — Efficacy of a Toothpaste Containing Hydrogen Peroxide as Compared to a Regular Fluoride Toothpaste Without Hydrogen Pero · Phase 3 · completed
- NCT07225478 — Clinical Study to Evaluate the Tooth Whitening Efficacy of a New NextGen In-office Whitening System · Phase 3 · completed
- NCT07224828 — The Efficacy of a Battery Toothbrush in the Reduction of Established Plaque and Gingivitis · Phase 3 · completed
- NCT07134231 — Clinical Study to Evaluate the Anti-cavity Efficacy of Three Dentifrices: An In Situ Model · Phase 3 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06954779 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Colgate Palmolive
- Last refreshed: 2 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06954779.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing