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NCT06933641
Regional Blocks for Lumbar Disc Surgery Analgesia
NA trial testing Regional Analgesia in Analgesia in 180 participants. Completed in 1 January 2025.
1 December 2024
Quick facts
| Lead sponsor | Erzincan University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 180 |
| Start date | 1 June 2024 |
| Primary completion | 1 December 2024 |
| Estimated completion | 1 January 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Regional Analgesia
Conditions studied
- Analgesia — all drugs for Analgesia →
Sponsor
Erzincan University
Who can join
Adults 18 to 65, any sex, with Analgesia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Objective The goal of this prospective randomized controlled experiment was comparing the analgesic efficacy, opioid needs, and adverse effect profiles of Paravertebral Block (PVB), Thoracolumbar Interfascial Plane Block (TLIP), and Retrolaminar Block (RLB) in patients undergoing lumbar disc herniation surgery. Methods 180 adults (ASA I-III) undergoing elective lumbar disc herniation surgery made up this single-center study. Among the exclusion criteria were coagulation problems, injection site infection, allergy to local anesthetics, and incapacity to provide informed consent. Patients were randomly assigned into four groups: Control (systemic analgesia only), PVB, TLIP, and RLB (45 patients per group). An expert anesthesiologist supervised the ultrasonography during each block. The Visual Analog Scale (VAS) was used to measure postoperative pain at 0, 1, 2, 6, 12, and 24 hours after surgery. This was the primary outcome. Motor block incidence, rescue morphine consumption, and Quality of Recovery-40 (QoR-40) scores at 24 hours were secondary objectives. Unfavorable incidents were noted. ANOVA and Kruskal-Wallis tests (p\<0.05) were used to examine the data.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Comparison of paravertebral, thoracolumbar interfascial plane, and retrolaminar blocks for postoperative analgesia in lumbar disc herniation surgery: A randomized controlled trial.
Tas HG, Akyol F, Somunkiran M. · · 2026 · PMID 41517760 · DOI 10.1097/md.0000000000047141
Verify or expand the search:
- PubMed search for NCT06933641
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06933641 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Erzincan University
- Last refreshed: 18 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06933641.
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