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NCT06932237: PASC

Immune-mediated Pathogenic Mechanisms of Neuro-PASC in Veterans

Recruiting now Last updated 31 March 2026
What this trial tests

trial in Neuro-PASC in 200 participants. Currently enrolling.

Timeline
20 February 2025
Primary endpoint
31 March 2028
31 March 2028

Quick facts

Lead sponsorVA Office of Research and Development
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment200
Start date20 February 2025
Primary completion31 March 2028
Estimated completion31 March 2028
Sites2 locations across United States

Conditions studied

Sponsor

VA Office of Research and Development — full company profile →

Who can join

Adults 18 to 80, any sex, with Neuro-PASC or Long COVID. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Mental health symptoms, including cognitive impairment ("brain fog"), following COVID-19 are of great concern to Veterans. This research seeks to advance understanding of the long-term effects of COVID-19 on neuropsychiatric and neurological functions, identifying clinically relevant biomarkers and directions for developing and testing therapeutic interventions. To accomplish these objectives the investigators are conducting a longitudinal study at two VA medical centers to: 1) assess and monitor cognitive function and psychiatric symptoms in Veterans post-COVID; 2) evaluate biomarkers of inflammation and signaling pathways associated with viral infection and neuropsychiatric function; and 3) integrate neuropsychiatric and neurological findings with biological data to identify biomarkers and clinical endpoints associated with disease progression or severity, as well as those for promoting brain repair and attenuating those symptoms.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other VA Office of Research and Development trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06932237.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing