NCT06921577 (dimensions) is a NA clinical trial of antimicrobial agent in Denture Stomatitis, sponsored by Tanta University.

Who is sponsoring NCT06921577?

NCT06921577 is sponsored by Tanta University.

What drugs are being tested in NCT06921577?

Interventions in NCT06921577: antimicrobial agent.

What condition does NCT06921577 study?

NCT06921577 studies Denture Stomatitis.

Is NCT06921577 still recruiting?

NCT06921577 is currently completed. Last updated 10 April 2025.

Last reviewed 2025-04-10 · How we verify

NCT06921577: dimensions

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Clinical and Microbial Study of Reinforced 3D Printed Maxillary Denture Base Resin

Completed NA Last updated 10 April 2025

What this trial tests

NA trial testing antimicrobial agent in Denture Stomatitis in 24 participants. Completed in 10 August 2024.

Timeline

10 February 2023

Primary endpoint
20 July 2024

10 August 2024

Quick facts

Lead sponsor	Tanta University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	sequential
Masking	none
Primary purpose	supportive care
Enrollment	24
Start date	10 February 2023
Primary completion	20 July 2024
Estimated completion	10 August 2024
Sites	1 location across Egypt

Drugs / interventions tested

antimicrobial agent — full drug profile →

Conditions studied

Denture Stomatitis — all drugs for Denture Stomatitis →

Sponsor

Tanta University

Who can join

Adults 50 to 70, any sex, with Denture Stomatitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Statement of problem: 3D printed denture base resin is needed to reinforce Purpose: To evaluate the effects of adding nano-ZrO2 and nano-TiO2 on microbial colonization and patient satisfaction with 3D-printed maxillary complete dentures. Materials and Methods: Twenty-four patients who needed complete dentures were randomly distributed into three equal groups. Group I: Patients used maxillary complete dentures 3D printed without additives. Group II: Patients used maxillary complete dentures 3D after reinforcement by Nano-ZrO2 (0.4%) by Wt. Group III: Patients used maxillary complete dentures 3D printed after reinforcement by Nano-TiO2 (0.4%) by Wt. For microbial evaluation, a cotton swab was taken from the mucosa and the intaglio surface of maxillary dentures, and microbial colonization was evaluated by calculating the number of colony-forming units of S. aureus on mannitol salt agar plates and C. albicans on Sabouraud's dextrose agar plates after 48 hours of incubation at insertion, 6 months, 12 months and 18 months. Patient satisfaction was evaluated 15 days after insertion and at 6, 12, and 18 months. The values of microbial colonization and patient satisfaction were analyzed via repeated-measures ANOVA followed by Tukey's multiple comparison test.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Clinical and microbial study of reinforced 3D-printed maxillary denture base resin: a randomized trial.
Ahmed Teama EM, Amin Rashad HM, Mohamed Shakal EAE, Hegazy EE. · · 2025 · PMID 40676540 · DOI 10.1186/s12903-025-06601-2
Clinical and microbial study of reinforced 3D printed maxillary denture base resin: A randomized trial
Teama EMA, Rashad HMA, Shakal EAM, Hegazy EEA. · · 2025 · DOI 10.21203/rs.3.rs-6506974/v1

Verify or expand the search:

Other recruiting trials for Denture Stomatitis

Currently open trials in the same condition.

NCT06395116 — Microbial Adhesion and Biofilm Formation on Denture Base Materials · active not recruiting

Other Tanta University trials

Trials by the same sponsor.

NCT07398651 — Apremilast and Adalimumab in Psoriatic Arthritis Patients · NA · not yet recruiting
NCT06966856 — This Randomized, Clinical Trial Evaluates the Efficacy of Oral Versus Sublingual Vitamin B12 Supplementation in Correcti · Phase 3 · not yet recruiting
NCT07334197 — Effect of Melatonin on Left Ventricular Reverse Remodeling and Inflammation in Peripartum Cardiomyopathy · NA · not yet recruiting
NCT07498998 — Glucocorticoid, Ozone and 5% Dextrose Local Injection for Pain Relief in Carpal Tunnel Syndrome · NA · not yet recruiting
NCT07114250 — Comparative Study Between Spinal Anesthesia Versus General Anesthesia in Supine Percutaneous Nephrolithotomy Operation · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06921577 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Tanta University
Last refreshed: 10 April 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06921577.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing