Who is sponsoring NCT06879600?

NCT06879600 is sponsored by Nguyen Dang Thu.

What drugs are being tested in NCT06879600?

Interventions in NCT06879600: High-flow nasal cannula therapy application, Traditional facemask.

What condition does NCT06879600 study?

NCT06879600 studies High-flow Nasal Cannula, Oxygenation, General Anesthesia, Induction Anesthesia, Emergency Surgery Patients, Full Stomach.

Is NCT06879600 still recruiting?

NCT06879600 is currently recruiting now. Last updated 17 March 2025.

Last reviewed 2025-03-17 · How we verify

NCT06879600: HFNC

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

High-Flow Nasal Oxygen for Preoxygenation in Emergency Surgery Patients With Full Stomachs

Recruiting now NA Last updated 17 March 2025

What this trial tests

NA trial testing High-flow nasal cannula therapy application in High-flow Nasal Cannula in 200 participants. Currently enrolling.

Timeline

19 July 2023

Primary endpoint
15 December 2026

31 December 2026

Quick facts

Lead sponsor	Nguyen Dang Thu
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	200
Start date	19 July 2023
Primary completion	15 December 2026
Estimated completion	31 December 2026
Sites	1 location across Vietnam

Drugs / interventions tested

High-flow nasal cannula therapy application
Traditional facemask

Conditions studied

High-flow Nasal Cannula — all drugs for High-flow Nasal Cannula →
Oxygenation — all drugs for Oxygenation →
General Anesthesia — all drugs for General Anesthesia →
Induction Anesthesia — all drugs for Induction Anesthesia →

Sponsor

Nguyen Dang Thu

Who can join

18 and older, any sex, with High-flow Nasal Cannula or Oxygenation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Patients with full stomachs face a high risk of regurgitation and aspiration under general anesthesia. To minimize the time between the loss of airway protective reflexes and successful tracheal intubation, rapid sequence induction intubation is commonly used. However, these patients are particularly vulnerable to hypoxemia during anesthesia induction, especially in emergency cases. Pre-oxygenation before induction is crucial for ensuring patient safety during apnea. High-flow nasal oxygen (HFNO) therapy, which consists of an air/oxygen blender, an active humidifier, and a single heated circuit, has recently gained widespread use in intensive care units (ICUs) for managing hypoxemic respiratory failure. HFNC can deliver a constant fraction of inspired oxygen (FiO₂) from 0.21 to 1.0 at high flow rates (up to 60 L/min or higher). Its advantages include generating continuous positive airway pressure, reducing anatomical dead space, improving ventilation-perfusion matching, enhancing mucociliary clearance, and decreasing the work of breathing. Given these benefits, HFNO has the potential to improve pre-oxygenation before and during anesthesia induction in emergency surgery patients with full stomachs.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

High-flow nasal oxygen versus face-mask ventilation for rapid sequence induction in non-elective surgical patients: a randomized controlled trial.
Lam ND, Son LDT, Phat TM, Thu ND, et al · · 2026 · PMID 41620676 · DOI 10.1186/s12871-026-03654-w

Verify or expand the search:

Other recruiting trials for High-flow Nasal Cannula

Currently open trials in the same condition.

NCT06425406 — Application of HFNC for the Prevention of Hypoxemia During Perioperative Anesthetic-induced Intubation in Children: A Ra · NA · recruiting
NCT06582459 — Efficacy and Safety of High-Flow Nasal Cannula Versus Noninvasive Ventilation for Pulmonary Arterial Hypertension-Associ · active not recruiting
NCT05526534 — A RCT on the Preventive Effect of HFNC on Postoperative Pulmonary Complications in Patients With Gynecologic Neoplasms · NA · recruiting
NCT06375538 — Ultrasound Evaluations of Diaphragm and Intercostal Muscle to Predict the Failure of High-Flow Nasal Cannula Therapy · recruiting

Other Nguyen Dang Thu trials

Trials by the same sponsor.

NCT07313644 — EIT-Guided PEEP Optimization in Trauma and Postoperative ARDS · NA · recruiting
NCT06850844 — Recruitment Maneuvers and PEEP-guided Electrical Impedance Tomography for Abdominal Laparoscopic Surgery Patients · NA · recruiting
NCT06260826 — CPAP on Oxygenation and Pulmonary Function in Elderly Patients After Major Open Abdominal Surgery · NA · completed
NCT06101407 — Univent Tube for Thoracoscopic Thymectomy in Myasthenic Patients · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06879600 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Nguyen Dang Thu
Last refreshed: 17 March 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06879600.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing