Last reviewed · How we verify
NCT06875609
ctDNA in Cutaneous Squamous Cell Carcinoma
trial testing Blood and Tissue Collection in Cutaneous Squamous Cell Carcinoma in 60 participants. Currently enrolling.
30 April 2028
Quick facts
| Lead sponsor | Massachusetts Eye and Ear Infirmary |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 60 |
| Start date | 24 March 2025 |
| Primary completion | 30 April 2028 |
| Estimated completion | 30 April 2029 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Blood and Tissue Collection
Conditions studied
- Cutaneous Squamous Cell Carcinoma — all drugs for Cutaneous Squamous Cell Carcinoma →
Sponsor
Massachusetts Eye and Ear Infirmary — full company profile →
Who can join
18 and older, any sex, with Cutaneous Squamous Cell Carcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to test the potential for a liquid biopsy assay to detect residual disease after surgery in patients with cutaneous squamous cell carcinoma as well as the potential for this assay to monitor response to immunotherapy treatment.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Liquid biopsy - a narrative review with an update on current US governmental clinical trials targeting immunotherapy.
Shen F, Zailaie SA, Chiu B, Magliocco A, et al · · 2025 · cited 2× · PMID 40772765 · DOI 10.1080/20565623.2025.2527598 -
Novel Immunotherapeutic Approaches for Patients with Head and Neck Cutaneous Squamous Cell Carcinoma.
Khorasanchi A, Hasanov M, Wu R, Alsharif H, et al · · 2026 · PMID 41930152 · DOI 10.32604/or.2026.069012
Verify or expand the search:
- PubMed search for NCT06875609
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Blood and Tissue Collection
Trials testing the same drug.
- NCT03108885 — Measuring Cell Free DNA During the Course of Treatment for Esophageal Cancer as a Marker of Response and Recurrence · terminated
Other recruiting trials for Cutaneous Squamous Cell Carcinoma
Currently open trials in the same condition.
- NCT07288073 — TIL Therapy in cSCC and MCC · Phase 2 · recruiting
- NCT07402616 — Ex Vivo Cutaneous SCC · NA · recruiting
- NCT06567314 — Phase 2 Study of Ivonescimab in Patients With Cutaneous Squamous Cell Carcinoma · Phase 2 · recruiting
- NCT06659146 — Thermotherapy in Addition to SOC Palliative Radiotherapy · NA · recruiting
- NCT06536946 — B-catenin in Cutaneous Squamous Cell Carcinoma and Its Mimickers · recruiting
Other Massachusetts Eye and Ear Infirmary trials
Trials by the same sponsor.
- NCT06926478 — Subconjunctival Humira for Boston Keratoprosthesis · Phase 1 · not yet recruiting
- NCT06425419 — The Safety and Efficacy of Intravitreal Topotecan for the Treatment of Proliferative Vitreoretinopathy · Phase 1 · not yet recruiting
- NCT07383701 — Lactiplantibacillus Plantarum 299v Probiotic Supplementation in Patients With Diabetic Macular Edema · Phase 2 · not yet recruiting
- NCT06688578 — Testing Effectiveness of a Stochastic Noise Stimulator to Immediately Improve Balance and Gait · NA · recruiting
- NCT06753916 — ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06875609 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Massachusetts Eye and Ear Infirmary
- Last refreshed: 30 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06875609.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing