Last reviewed · How we verify
NCT03108885
Measuring Cell Free DNA During the Course of Treatment for Esophageal Cancer as a Marker of Response and Recurrence
trial testing Blood and Tissue Collection in Esophageal Neoplasm in 11 participants. Terminated before completion.
25 May 2020
Quick facts
| Lead sponsor | Mayo Clinic |
|---|---|
| Status | Terminated |
| Study type | OBSERVATIONAL |
| Enrollment | 11 |
| Start date | 1 October 2017 |
| Primary completion | 25 May 2020 |
| Estimated completion | 25 May 2020 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Blood and Tissue Collection
Conditions studied
- Esophageal Neoplasm — all drugs for Esophageal Neoplasm →
- Esophageal Neoplasms Malignancy Unspecified — all drugs for Esophageal Neoplasms Malignancy Unspecified →
- Esophageal Neoplasms Malignant — all drugs for Esophageal Neoplasms Malignant →
- Cancer of Esophagus — all drugs for Cancer of Esophagus →
Sponsor
Mayo Clinic
Who can join
19 and older, any sex, with Esophageal Neoplasm or Esophageal Neoplasms Malignancy Unspecified. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To prospectively collect blood and tumor tissue from esophageal cancer patients to identify specific esophageal cancer mutations that can be measured in the blood (cell free DNA) during the course of treatment as a marker of response and recurrence.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Exploring the clinical utility of liquid biopsy with cfDNA in cancer: A systematic review.
Ranganathan K, Kurian NS, Goswami HM, Rishi KD, et al · · 2024 · cited 5× · PMID 40027943 · DOI 10.1016/j.jlb.2024.100150 -
Current status and perspectives of genetic testing in gastrointestinal cancer (Review).
Matsuoka T, Yashiro M. · · 2024 · cited 4× · PMID 38058469 · DOI 10.3892/ol.2023.14155
Verify or expand the search:
- PubMed search for NCT03108885
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Blood and Tissue Collection
Trials testing the same drug.
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Other recruiting trials for Esophageal Neoplasm
Currently open trials in the same condition.
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- NCT00288119 — Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma · recruiting
- NCT00431756 — Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus · active not recruiting
- NCT06481449 — Definitive Radiotherapy for Cervical and Upper Thoracic Esophageal Cancer (ChC&UES): A Multi-center Real World Study · recruiting
Other Mayo Clinic trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03108885 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mayo Clinic
- Last refreshed: 22 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03108885.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing