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NCT06870903: ENDONOTE
Comparison of Transvaginal Paracervical and Transperitoneal Approaches in Lymphadenectomy During v-NOTES Surgery for Patients Diagnosed With Endometrial Cancer
NA trial testing Extraperitoneal(transvaginal paracervical sentinel lymphadenectomy) group lymphadenectomy in Endometrial Cancer in 52 participants. Currently enrolling.
31 December 2025
Quick facts
| Lead sponsor | Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 52 |
| Start date | 15 March 2025 |
| Primary completion | 31 December 2025 |
| Estimated completion | 1 March 2026 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Extraperitoneal(transvaginal paracervical sentinel lymphadenectomy) group lymphadenectomy
- Transperitoneal lymphadenectomy
Conditions studied
- Endometrial Cancer — all drugs for Endometrial Cancer →
- Lymphadenectomy — all drugs for Lymphadenectomy →
- Sentinel Lymph Node Biopsy — all drugs for Sentinel Lymph Node Biopsy →
- Minimally Invasive Surgical Procedures — all drugs for Minimally Invasive Surgical Procedures →
Sponsor
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Who can join
Adults 18 to 85, female only, with Endometrial Cancer or Lymphadenectomy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to compare two types of lymphadenectomy (transperitoneal vs. paracervical) during the lymphadenectomy phase of endometrial cancer staging surgery performed using V-NOTES, a new and advanced technique. This study seeks to optimize the V-NOTES technique for endometrial cancer staging. This randomized, prospective, controlled study will include patients diagnosed with endometrial cancer via histology, following physical examination and imaging, and who are electively scheduled for the V-NOTES endometrial cancer staging procedure. Patients will be randomized into two groups: the transvaginal paracervical lymphadenectomy group and the transperitoneal lymphadenectomy group. The parameters related with surgical and functional outcomes will be compared in both groups.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06870903
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06870903 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
- Last refreshed: 20 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06870903.
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