NCT07306507 (VNOTES-TLH) is a NA clinical trial of vNOTES Hysterectomy in Hysterectomy, sponsored by Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital.

What drugs are being tested in NCT07306507?

Interventions in NCT07306507: vNOTES Hysterectomy, Total Laparoscopic Hysterectomy.

What condition does NCT07306507 study?

NCT07306507 studies Hysterectomy.

Is NCT07306507 still recruiting?

NCT07306507 is currently completed. Last updated 15 April 2026.

Last reviewed 2026-04-15 · How we verify

NCT07306507: VNOTES-TLH

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

vNOTES vs Laparoscopic Hysterectomy: Randomized Trial on Pain and Recovery"

Completed NA Last updated 15 April 2026

What this trial tests

NA trial testing vNOTES Hysterectomy in Hysterectomy in 90 participants. Completed in 10 April 2026.

Timeline

8 January 2026

Primary endpoint
9 April 2026

10 April 2026

Quick facts

Lead sponsor	Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	90
Start date	8 January 2026
Primary completion	9 April 2026
Estimated completion	10 April 2026
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

vNOTES Hysterectomy
Total Laparoscopic Hysterectomy

Conditions studied

Hysterectomy — all drugs for Hysterectomy →

Sponsor

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Who can join

Adults 18 to 75, female only, with Hysterectomy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study is a prospective, randomized controlled trial comparing two different minimally invasive hysterectomy techniques: vaginal natural orifice transluminal endoscopic surgery (vNOTES) and conventional total laparoscopic hysterectomy (TLH). The aim is to evaluate whether vNOTES provides better postoperative comfort and recovery by reducing pain, lowering opioid analgesic requirements, and improving early recovery outcomes. Approximately 80 women undergoing elective hysterectomy will be randomly assigned to either vNOTES or TLH. All surgeries will be performed under standardized general anesthesia by the same experienced surgical team. Postoperative pain management will follow an identical protocol for all patients. Primary outcomes include postoperative pain scores (at 12 and 24 hours) and total opioid consumption. Secondary outcomes include Quality of Recovery-15 (QoR-15) scores, fatigue scores, time to first mobilization, time to first flatus, and length of hospital stay. The results of this study may help identify which hysterectomy technique offers better patient-centered recovery and postoperative comfort.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Hysterectomy

Currently open trials in the same condition.

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Other Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital trials

Trials by the same sponsor.

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NCT07325331 — Lullaby vs White Noise vs Silence in Pediatric MRI Sedation · NA · completed
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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07306507 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Last refreshed: 15 April 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07306507.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing