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NCT06865378
The Correlation Between Intraoperative End Tidal Carbon Dioxide, Perfusion Index and Pulse Variability Index on Postoperative Nausea Vomiting and Pain
trial testing Carbon dioxide (CO2) gas insufflation in Postoperative Nausea and Vomiting in 90 participants. Enrolling by invitation.
15 December 2025
Quick facts
| Lead sponsor | Naime Yalçın |
|---|---|
| Status | ENROLLING BY INVITATION |
| Study type | OBSERVATIONAL |
| Enrollment | 90 |
| Start date | 15 March 2021 |
| Primary completion | 15 December 2025 |
| Estimated completion | 31 December 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Carbon dioxide (CO2) gas insufflation — full drug profile →
Conditions studied
- Postoperative Nausea and Vomiting — all drugs for Postoperative Nausea and Vomiting →
- Postoperative Pain, Acute — all drugs for Postoperative Pain, Acute →
- End Tidal Carbon Dioxide — all drugs for End Tidal Carbon Dioxide →
- Perfusion Index and Pleth Variability Index — all drugs for Perfusion Index and Pleth Variability Index →
Sponsor
Naime Yalçın
Who can join
Adults 20 to 65, female only, with Postoperative Nausea and Vomiting or Postoperative Pain, Acute. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Postoperative pain, which is frequently encountered in laparoscopic operations, has been examined in different studies with end tidal CO2 (end tidal carbon dioxide), total insufflated gas amount and PI (Perfusion index) parameters. PONV (postoperative nausea and vomiting), which is encountered more frequently than pain in the postoperative period, has been examined in relation to end tidal CO2. In this study, it was aimed to evaluate the development of postoperative pain and PONV, which affect recovery and patient comfort, by comparing the relationship between end tidal CO2, PI and PVI (Pulse variability index).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06865378
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Carbon dioxide (CO2) gas insufflation
Trials testing the same drug.
- NCT03287687 — Safety and Efficacy of CO2 for Endoscopy · Phase 4 · completed
Other recruiting trials for Postoperative Nausea and Vomiting
Currently open trials in the same condition.
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- NCT07242209 — Sugammadex and Menstrual Cycle in Postoperative Nausea and Vomiting · recruiting
- NCT07244575 — Association Between Preoperative Metformin Exposure and Postoperative Nausea and Vomiting in Patients Undergoing General · recruiting
- NCT06632184 — Peritoneal Lavage Using Saline or Saline With Ondansetron for Pain Control After Laparoscopic Cholecystectomy · Phase 4 · active not recruiting
- NCT07271147 — Effects of taVNS Combined With Dexmedetomidine on POVN · NA · recruiting
Other Naime Yalçın trials
Trials by the same sponsor.
- NCT06849661 — Do Preoperative Bilirubin Levels Affect Recovery and Hospital Stay After Sedation Anesthesia? · enrolling by invitation
- NCT06824935 — Evaluation of Perioperative Anesthesia Requirements of Outpatient Cataract Patients · enrolling by invitation
- NCT06810232 — Effects of General Health Risk Factors on Prolonged Hospital Stay · enrolling by invitation
- NCT06843031 — The Role of Perfusion Index in Defining Postoperative Shivering · active not recruiting
- NCT06837415 — Association Between Preoperative Anxiety and Blood Eosinophil Levels · enrolling by invitation
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06865378 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Naime Yalçın
- Last refreshed: 7 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06865378.
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