NCT06864234 (BEACON) is a Phase 4 clinical trial of Saline (NaCl) in Coronary Arterial Disease (CAD), sponsored by VZW Cardiovascular Research Center Aalst.

Who is sponsoring NCT06864234?

NCT06864234 is sponsored by VZW Cardiovascular Research Center Aalst.

What drugs are being tested in NCT06864234?

Interventions in NCT06864234: Saline (NaCl), Metoprolol Tartrate.

What condition does NCT06864234 study?

NCT06864234 studies Coronary Arterial Disease (CAD), Angina (Stable), Microvascular Circulation.

Is NCT06864234 still recruiting?

NCT06864234 is currently recruiting now. Last updated 14 July 2025.

Last reviewed 2025-07-14 · How we verify

NCT06864234: BEACON

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Beta-blockers on Coronary Flow and Resistance in Patients With ANOCA

Recruiting now Phase 4 Last updated 14 July 2025

What this trial tests

Phase 4 trial testing Saline (NaCl) in Coronary Arterial Disease (CAD) in 46 participants. Currently enrolling.

Timeline

3 July 2025

Primary endpoint
31 December 2025

31 December 2025

Quick facts

Lead sponsor	VZW Cardiovascular Research Center Aalst
Phase	Phase 4
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	basic science
Enrollment	46
Start date	3 July 2025
Primary completion	31 December 2025
Estimated completion	31 December 2025
Sites	1 location across Belgium

Drugs / interventions tested

Saline (NaCl) — full drug profile →
Metoprolol Tartrate — full drug profile →

Conditions studied

Coronary Arterial Disease (CAD) — all drugs for Coronary Arterial Disease (CAD) →
Angina (Stable) — all drugs for Angina (Stable) →
Microvascular Circulation — all drugs for Microvascular Circulation →

Sponsor

VZW Cardiovascular Research Center Aalst — full company profile →

Who can join

18 and older, any sex, with Coronary Arterial Disease (CAD) or Angina (Stable). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this clinical trial is to learn whether beta-blockers can improve coronary blood flow and reduce resistance in patients with angina and no obstructive coronary arteries (ANOCA). The main questions it aims to answer are: * Do beta-blockers improve coronary blood flow in patients with ANOCA? * Do beta-blockers reduce coronary microvascular resistance in these patients? Researchers will compare a beta-blocker to a placebo to see if the medication has measurable effects on coronary circulation. Participants will: * Receive a beta-blocker or a placebo * Undergo specialized heart tests (such as coronary flow and resistance measurements) before and after treatment.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Coronary Arterial Disease (CAD)

Currently open trials in the same condition.

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NCT07025148 — Dual Antiplatelet Therapy Escalation From Standard-dose Clopidogrel to Low-Dose Prasugrel in Patients With High Bleeding · Phase 4 · recruiting
NCT07093788 — Super High-pressure Balloon Versus Intravascular Lithotripsy to Prepare Severely Calcified Coronary Lesions · NA · recruiting
NCT07041359 — Pre-trial of Clinical Trial of Traditional Chinese Medicine Treatment for Elderly Patients With Coronary Heart Disease W · Phase 4 · recruiting

Other VZW Cardiovascular Research Center Aalst trials

Trials by the same sponsor.

NCT06823843 — The Effect of Sublingual Nitroglycerin on Absolute Coronary Blood Flow · Phase 4 · completed
NCT04789317 — Pullback Pressure Gradient (PPG) Global Registry · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06864234 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by VZW Cardiovascular Research Center Aalst
Last refreshed: 14 July 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06864234.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing