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NCT06860685
Trial of Gum Chewing to Enhance the Restoration of Intestinal Motility in Colorectal Cancer Surgery
Phase 1, PHASE2 trial testing gum chewing in Colorectal Cancer (CRC) in 292 participants. Not yet recruiting.
31 July 2025
Quick facts
| Lead sponsor | Sichuan Cancer Hospital and Research Institute |
|---|---|
| Phase | Phase 1, PHASE2 |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 292 |
| Start date | 1 March 2025 |
| Primary completion | 31 July 2025 |
| Estimated completion | 31 August 2025 |
| Sites | 1 location across China |
Drugs / interventions tested
- gum chewing — full drug profile →
Conditions studied
- Colorectal Cancer (CRC) — all drugs for Colorectal Cancer (CRC) →
Sponsor
Sichuan Cancer Hospital and Research Institute
Who can join
Adults 18 to 90, any sex, with Colorectal Cancer (CRC). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Surgery is one of the most frequent treatments of colorectal cancer. However, delayed restoration of intestinal motility is a common phenomenon in patients who undergo colorectal surgery, and may reduce comfort, prevent the early hospital discharge of patients and increase healthcare costs. Gum chewing is a kind of safe and easily accessible sham feeding to stimulate intestinal motility. In addition, prediction models were used to estimate the risk of delayed restoration of intestinal motility after colorectal surgery. Thus, this study is an External Controlled trial that will determine whether stratified application of gum chewing by risk prediction model will enhance restoration of intestinal motility and reduce healthcare costs in paitents undergoing open or laparoscopic colorectal surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06860685
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Related trials
Other trials of gum chewing
Trials testing the same drug.
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- NCT06029790 — The Effect of Chewing Gum on Nausea, Vomiting and Bowel Function After Colorectal Surgery · NA · completed
- NCT02649153 — Effect of Smoked Plum and Chewing Gum on Postoperative Bowel Function Following Hepatic Resection · Phase 3 · completed
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Currently open trials in the same condition.
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Other Sichuan Cancer Hospital and Research Institute trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06860685 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sichuan Cancer Hospital and Research Institute
- Last refreshed: 6 March 2025
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