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NCT06857513: PICUS2
Post-ICU Syndrome Over Time in Patients With Respiratory Failure
trial testing Questionnaire and Physical Exam in Post-Intensive Care Syndrome in 90 participants. Not yet recruiting.
31 December 2025
Quick facts
| Lead sponsor | Dr. Negrin University Hospital |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 90 |
| Start date | 1 October 2025 |
| Primary completion | 31 December 2025 |
| Estimated completion | 30 January 2026 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Questionnaire and Physical Exam — full drug profile →
- EuroQol 5-Dimension 3-Level
- EuroQol Visual Analogue Scale (EQ-VAS)
Conditions studied
- Post-Intensive Care Syndrome — all drugs for Post-Intensive Care Syndrome →
- Quality of Life — all drugs for Quality of Life →
Sponsor
Dr. Negrin University Hospital
Who can join
18 and older, any sex, with Post-Intensive Care Syndrome or Quality of Life. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Intensive Care Units (ICU) stabilize and maintain vital functions in critically ill patients, optimizing their survival. However, patients with prolonged stays may develop Post-ICU syndrome , characterized by physical, cognitive and psychological dysfunctions. This syndrome considerably affects the quality of life of patients. The risk of post-ICU syndrome is associated with factors such as advanced age, delirium, prolonged sedation and mechanical ventilation. The main objective of this study is to assess the temporal evolution of post-ICU syndrome in patients who required mechanical ventilation for more than 48 hours, analyzing its incidence, associated risk factors and the impact on their long-term quality of life. This cross-sectional study evaluates the presence of post-ICU syndrome in 2025 in patients who have been admitted to the ICU during 2021 and 2024 who required invasive mechanical ventilation for more than 48 hours. Of this total, deceased persons, those who did not give their consent, and minors will not be included.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06857513
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Post-Intensive Care Syndrome
Currently open trials in the same condition.
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Other Dr. Negrin University Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06857513 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Dr. Negrin University Hospital
- Last refreshed: 8 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06857513.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing