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NCT06847594
An Evaluation the Effect of Superhydration Versus Dextrose 10% for Prevention of Post Operative Nausea and Vomiting After Laparoscopic Cholecystectomy (Prospective Randomised Controlled Study)
Phase 3 trial testing ringer lactate (20ml/kg) in Postoperative Nausea and Vomiting (PONV) in 204 participants. Completed in 10 October 2024.
25 September 2024
Quick facts
| Lead sponsor | Ain Shams University |
|---|---|
| Phase | Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 204 |
| Start date | 25 February 2024 |
| Primary completion | 25 September 2024 |
| Estimated completion | 10 October 2024 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- ringer lactate (20ml/kg) — full drug profile →
- Dextrose 10% — full drug profile →
Conditions studied
- Postoperative Nausea and Vomiting (PONV) — all drugs for Postoperative Nausea and Vomiting (PONV) →
Sponsor
Ain Shams University
Who can join
Adults 21 to 60, any sex, with Postoperative Nausea and Vomiting (PONV). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to learn if Dextrose 10% or superhydration works to prevent postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy. . The main questions it aims to answer are: Does Dextrose 10% or superhydration lower the number of times participants gets an episode of nausea and vomititng after laparoscopic cholecystectomy surgery? Researchers will compare Dextrose 10% versus superhydration to a placebo (a look-alike substance that contains no drug) to see if glucose 10% or superhydation can work to prevent postoperative nausea and vomiting. Participants will: Take Dextrose 10% or superhydration or a placebo in the operation monitored for 4 hours after surgery to check on their nausea and vomiting state
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06847594
- Europe PMC full search
- ASCO Meeting Library
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Related trials
Other recruiting trials for Postoperative Nausea and Vomiting (PONV)
Currently open trials in the same condition.
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- NCT07148063 — Inflammatory Biomarkers as Predictors of PONV Following Pediatric Orchiopexy · recruiting
- NCT07201883 — Chewing Gum vs. Ondansetron as Rescue Treatment for PONV in Female Patients · Phase 1 · active not recruiting
Other Ain Shams University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06847594 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
- Last refreshed: 26 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06847594.
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