Last reviewed · How we verify
NCT06805188
Clinical Study of Acupuncture Treatment of Knee Osteoarthritis
NA trial testing Acupuncture in Osteoarthritis of the Knees in 350 participants. Currently enrolling.
5 January 2026
Quick facts
| Lead sponsor | Wu zenan |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | single group |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 350 |
| Start date | 15 February 2025 |
| Primary completion | 5 January 2026 |
| Estimated completion | 5 January 2026 |
| Sites | 1 location across China |
Drugs / interventions tested
- Acupuncture — full drug profile →
- Sham acupuncture
Conditions studied
- Osteoarthritis of the Knees — all drugs for Osteoarthritis of the Knees →
- Osteoarthritis (OA) of the Knee — all drugs for Osteoarthritis (OA) of the Knee →
- Osteoarthritis — all drugs for Osteoarthritis →
Sponsor
Wu zenan
Who can join
Adults 18 to 70, any sex, with Osteoarthritis of the Knees or Osteoarthritis (OA) of the Knee. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The main question of this study was to evaluate the efficacy and safety of acupuncture in the treatment of knee osteoarthritis (KOA) through a single-blind, randomized controlled trial divided into two groups. Patients in both groups received a total of 24 acupuncture treatments over an 8-week period. The differences in knee NRS score, WOMAC index, walking test, mental health assessment and other indicators between the acupuncture group and the sham acupuncture group before and after treatment were compared to provide high-quality evidence to support the effectiveness of acupuncture in treating KOA.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Efficacy and Safety of Acupuncture at Sensitized Acupoints for Knee Osteoarthritis: Protocol for a Multicenter, Single-Blind Randomized Controlled Trial.
Wu Z, Hu Z, Xu Z, Xiao T, et al · · 2025 · cited 1× · PMID 40990366 · DOI 10.2196/77336
Verify or expand the search:
- PubMed search for NCT06805188
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Acupuncture
Trials testing the same drug.
- NCT07522567 — Efficacy of Acupuncture on Chronic Tinnitus and Its Association With Auditory Brainstem Response Measures · NA · not yet recruiting
- NCT07575334 — Acupuncture Therapy for Sudden Sensorineural Hearing Loss · NA · recruiting
- NCT07522710 — Clinical Study on Intensive Multi-acupuncture in the Treatment of Neck and Shoulder Myofascial Pain Syndrome · NA · not yet recruiting
- NCT07505927 — Acupuncture for Postoperative Gastric Emptying Delay · NA · not yet recruiting
- NCT07410793 — Acupuncture With Chinese Herbal Cream Compare With Acupuncture With Calcipotriol in Plaque Psoriasis. · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06805188 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Wu zenan
- Last refreshed: 3 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06805188.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing