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NCT06782204
Variability of Sulfotransferase Activity in Humans: an Approach to Improve Predictive Drug Response Part II: Analysis of Interindividual Variation in Hypertensive Patients
Phase 1 trial testing Paracetamol in Hypertension in 7 participants. Completed in 1 April 2021.
1 January 2021
Quick facts
| Lead sponsor | Hospital da Luz, Portugal |
|---|---|
| Phase | Phase 1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 7 |
| Start date | 1 July 2020 |
| Primary completion | 1 January 2021 |
| Estimated completion | 1 April 2021 |
| Sites | 1 location across Portugal |
Drugs / interventions tested
- Paracetamol (Paracetamol) — full drug profile →
Conditions studied
- Hypertension — all drugs for Hypertension →
Sponsor
Hospital da Luz, Portugal
Who can join
Adults 18 to 90, any sex, with Hypertension. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
An open-label, single center, nonrandomized clinical study in hypertensive patients, with intervention, over a 5-week period. After written informed consent, subjects will undergo screening evaluations, including blood and urine sampling (Visit 1). After visit 1, subjects who meet the selection criteria will enter a run-in period where they will receive paracetamol 1g tablet and collect blood and urine samples 2 hours afterwards (visit 2). A final visit for safety assessment will take place at week 5 (visit 3). Blood and urine samples will be used to quantify paracetamol and its metabolites.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06782204
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Hypertension
Currently open trials in the same condition.
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Other Hospital da Luz, Portugal trials
Trials by the same sponsor.
- NCT05954689 — Femoral Artery Block for Reduction of Tourniquet Induced Hypertension · NA · unknown
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- NCT03182595 — Variability of Sulfotransferase 1A1 Activity in Humans: an Approach to Improve Predictive Drug Response - Part I: Analys · Phase 1 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06782204 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hospital da Luz, Portugal
- Last refreshed: 17 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06782204.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing