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NCT06763198

Genetic Polymorphisms Associated With the Risk of Pancreatitis in Patients With Alcohol Related Cirrhosis.

Not yet recruiting Last updated 22 January 2025
What this trial tests

trial in Alcohol-related Liver Disease in 150 participants. Not yet recruiting.

Timeline
25 January 2025
Primary endpoint
31 January 2026
31 January 2026

Quick facts

Lead sponsorInstitute of Liver and Biliary Sciences, India
StatusNot yet recruiting
Study typeOBSERVATIONAL
Enrollment150
Start date25 January 2025
Primary completion31 January 2026
Estimated completion31 January 2026
Sites1 location across India

Conditions studied

Sponsor

Institute of Liver and Biliary Sciences, India

Who can join

18 and older, any sex, with Alcohol-related Liver Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Alcohol is a known risk factor for both pancreatitis and cirrhosis. However, not all patients with alcohol related cirrhosis develop pancreatitis. It is not known which patients with alcohol-related cirrhosis develop symptomatic or clinically inapparent pancreatitis (Acute or Chronic Pancreatitis).There is no data whether genetic polymorphisms predispose patients with alcohol-related cirrhosis to additional pancreatic injury. There is no data on the spectrum of clinical and subclinical pancreatic changes (structural and functional) in patients with alcohol-related cirrhosis, and their genotypic correlates.This study aims to determine pancreatitis-related gene variants among patients with alcohol-related cirrhosis, with and without pancreatitis. We also aim to study differences in nutritional and functional parameters among alcoholic cirrhosis with and without chronic pancreatitis and also define the relationship of genetic polymorphisms with the pancreatic phenotype. Consecutive patients with alcohol related cirrhosis will be screened for changes of pancreatitis on CT/MR/EUS. Those with and without pancreatitis will be compared with respect to demographic, clinical, genotype, nutritional status .We will also be including a group of MAFLD/Cryptogenic cirrhosis for genotypic and phenotypic comparison.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Alcohol-related Liver Disease

Currently open trials in the same condition.

Other Institute of Liver and Biliary Sciences, India trials

Trials by the same sponsor.

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Data sources for this page

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