NCT06305624 (IMPACT-ALD) is a NA clinical trial of Connections App in Alcohol Use Disorder, sponsored by University of Wisconsin, Madison.

Who is sponsoring NCT06305624?

NCT06305624 is sponsored by University of Wisconsin, Madison.

What drugs are being tested in NCT06305624?

Interventions in NCT06305624: Connections App.

What condition does NCT06305624 study?

NCT06305624 studies Alcohol Use Disorder, Alcohol-related Liver Disease.

Is NCT06305624 still recruiting?

NCT06305624 is currently recruiting now. Last updated 14 April 2026.

Last reviewed 2026-04-14 · How we verify

NCT06305624: IMPACT-ALD

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Implementation of Mobile-based Programs for Alcohol Cessation in Treatment of Alcohol-associated Liver Disease

Recruiting now NA Last updated 14 April 2026

What this trial tests

NA trial testing Connections App in Alcohol Use Disorder in 298 participants. Currently enrolling.

Timeline

1 June 2024

Primary endpoint
31 October 2027

31 October 2027

Quick facts

Lead sponsor	University of Wisconsin, Madison
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	health services research
Enrollment	298
Start date	1 June 2024
Primary completion	31 October 2027
Estimated completion	31 October 2027
Sites	3 locations across United States

Drugs / interventions tested

Connections App

Conditions studied

Alcohol Use Disorder — all drugs for Alcohol Use Disorder →
Alcohol-related Liver Disease — all drugs for Alcohol-related Liver Disease →

Sponsor

University of Wisconsin, Madison

Who can join

18 and older, any sex, with Alcohol Use Disorder or Alcohol-related Liver Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This protocol describes a randomized controlled trial testing the effectiveness and implementability of the CHESS Health Connections smartphone application among patients with alcohol-associated liver disease (ALD) at two medical centers in Michigan and Wisconsin, in two types of clinics: general hepatology and multidisciplinary that offers care for advanced ALD alongside co-located, integrated mental health and substance abuse treatment. The long-term goal of this and future work is to prevent disease progression and promote healthy behaviors by improving the rate of abstinence among patients with ALD earlier in the course of their disease. 298 participants will be enrolled and can expect to be on study for up to 6 months.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Exploring Fit in a Mobile Health Intervention for Alcohol Use Disorder: Qualitative Study.
Jacobson N, Park LS, Pulvermacher A, Voelker S, et al · · 2025 · PMID 41086457 · DOI 10.2196/65218

Verify or expand the search:

Other recruiting trials for Alcohol Use Disorder

Currently open trials in the same condition.

NCT06860607 — Environment and Alcohol: A Pilot Study · Phase 1 · recruiting
NCT07325266 — Human Laboratory Study of Apremilast for Alcohol Use Disorder · Phase 2 · recruiting
NCT07046819 — Tirzepatide in MetALD · Phase 2 · recruiting
NCT07279558 — Cannabidiol and Alcohol Use Disorder Phenotypes · Phase 2 · recruiting
NCT07056894 — Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis · NA · recruiting

Other University of Wisconsin, Madison trials

Trials by the same sponsor.

NCT07440004 — Testing a Digital Mindfulness Program to Support People Experiencing Suicidal Thoughts · Phase 1 · recruiting
NCT07278466 — The COMParing App Support Strategies Study · NA · recruiting
NCT07475104 — Redesigning Surgical Care for Patients in Wisconsin · NA · enrolling by invitation
NCT07470723 — The ORIGIN-FH Study · NA · recruiting
NCT06975657 — Well-being Skills for Reentry · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06305624 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Wisconsin, Madison
Last refreshed: 14 April 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06305624.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing