Last reviewed · How we verify
NCT06763081: PGx-SImBA
Pharmacogenomics of Selective Serotonin Reuptake Inhibitor (SSRI)-Induced Behavioural Activation
trial testing Not applicable- observational study in Behavioral Activation in 160 participants. Currently enrolling.
31 December 2028
Quick facts
| Lead sponsor | University of Manitoba |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 160 |
| Start date | 1 March 2025 |
| Primary completion | 31 December 2028 |
| Estimated completion | 31 December 2030 |
| Sites | 2 locations across Canada |
Drugs / interventions tested
- Not applicable- observational study — full drug profile →
Conditions studied
- Behavioral Activation — all drugs for Behavioral Activation →
- Major Depressive Disorder — all drugs for Major Depressive Disorder →
- Anxiety Disorders — all drugs for Anxiety Disorders →
- Antidepressant Drug Adverse Reaction — all drugs for Antidepressant Drug Adverse Reaction →
Sponsor
University of Manitoba
Who can join
Adults 6 to 24, any sex, with Behavioral Activation or Major Depressive Disorder. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to identify and validate a panel of genetic markers associated with selective serotonin reuptake inhibitors (SSRI)-induced behavioural activation in children and youth with major depressive disorder (MDD), anxiety disorders, or obsessive-compulsive disorder (OCD) that could be used clinically to reduce the incidence of this adverse event and improve health outcomes.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06763081
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06763081 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Manitoba
- Last refreshed: 8 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06763081.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing