Last reviewed · How we verify
NCT06750887: CLEVER-BODY
Modifying Lumbar Flexion Pain Thresholds in Chronic LBP Using Virtual Reality and Visual-Proprioceptive Manipulation
trial testing Normal condition in Chronic Low Back Pain (CLBP) in 50 participants. Completed in 8 January 2025.
18 December 2024
Quick facts
| Lead sponsor | Cardenal Herrera University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 4 December 2024 |
| Primary completion | 18 December 2024 |
| Estimated completion | 8 January 2025 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Normal condition
- Understated condition
- OVERSTATED CONDITION
Conditions studied
- Chronic Low Back Pain (CLBP) — all drugs for Chronic Low Back Pain (CLBP) →
Sponsor
Cardenal Herrera University
Who can join
Adults 18 to 65, any sex, with Chronic Low Back Pain (CLBP). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study investigates the potential to modify movement-evoked pain in individuals with chronic low back pain (LBP) by manipulating visual proprioceptive feedback through virtual reality (VR). Fifty patients with non-specific chronic LBP are planned to participate. Participants perform lumbar spine flexions until pain onset under three conditions: accurate visual feedback (control), feedback showing 20% less movement (F-), and feedback showing 20% more movement (F+). Lumbar range of motion (ROM) is measured using a 3-space Fastrack motion analysis system. The study also explores whether individuals with higher pain levels, kinesiophobia, or catastrophising are more susceptible to VR feedback manipulation. Pain thresholds, pain intensity, kinesiophobia, and catastrophising levels are assessed.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Modifying lumbar flexion pain thresholds in patients with chronic low back pain through visual-proprioceptive manipulation with virtual reality: a cross-sectional study.
Jordán-López J, Arguisuelas MD, Doménech J, Peñalver-Barrios ML, et al · · 2025 · cited 1× · PMID 40537791 · DOI 10.1186/s12984-025-01664-2
Verify or expand the search:
- PubMed search for NCT06750887
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Chronic Low Back Pain (CLBP)
Currently open trials in the same condition.
- NCT07304076 — Clinical Research on the Comparative Effectiveness and Safety of JHG002 Therapy for Chronic Low Back Pain: A Multicenter · NA · recruiting
- NCT07298941 — Resilience Enhancement Following Sleep Treatment · Phase 2 · recruiting
- NCT07161661 — Chronic Low Back Pain and Osteopathic Manipulation Treatment · NA · recruiting
- NCT07215104 — A Prospective Evaluation of Spinal Cord Induced Muscle Stimulation (MuscleSCS) for the Treatment of Chronic Low Back Pai · NA · recruiting
- NCT07163117 — Lumber Stabilization Exercise Versus Back Endurance Exercise Among Female University Students · NA · recruiting
Other Cardenal Herrera University trials
Trials by the same sponsor.
- NCT07471269 — Online Pain Neuroscience Education For Fear Of Childbirth. · NA · recruiting
- NCT07373938 — Carotid Wall Texture as a Cardiovascular Risk Biomarker in Type 2 Diabetes Mellitus · recruiting
- NCT07499856 — Intradialytic Exercise Program Supported by Audiovisual Media Combined With Mindfulness · NA · enrolling by invitation
- NCT07275112 — Cross-cultural an Reliability and Validity Evaluation of TENDINS-A in Spain · completed
- NCT07133581 — Design and Validation of FEXO: A Playful Exercise Program for Institutionalized Frail Older Adults · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06750887 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cardenal Herrera University
- Last refreshed: 11 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06750887.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing