Last reviewed · How we verify
NCT06736925
Omega-3 Fatty Acids and Subconcussive Head Impacts
NA trial testing Omega-3 Fatty Acids (EPA plus DHA) in Subconcussive Head Impact in 208 participants. Currently enrolling.
31 May 2029
Quick facts
| Lead sponsor | Indiana University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 208 |
| Start date | 28 February 2025 |
| Primary completion | 31 May 2029 |
| Estimated completion | 31 May 2029 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Omega-3 Fatty Acids (EPA plus DHA) — full drug profile →
- Organic soybean oil
- Soccer Heading Model
Conditions studied
- Subconcussive Head Impact — all drugs for Subconcussive Head Impact →
- Omega-3 Fatty Acids — all drugs for Omega-3 Fatty Acids →
Sponsor
Indiana University
Who can join
Adults 18 to 30, any sex, with Subconcussive Head Impact or Omega-3 Fatty Acids. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of the proposed double-blind, randomized placebo-controlled trial is to understand how supplementation with fish oil \[docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA)\] promote brain health against soccer heading. The study involves taking DHA+EPA or placebo, questionnaires, blood draws, brain imaging, tests to evaluate heart function, and soccer headings.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Investigating omega-3 fatty acids' neuroprotective effects in repetitive subconcussive neural injury: Study protocol for a randomized placebo-controlled trial.
Beauregard LH, Bazarian JJ, Johnson BD, Cheng H, et al · · 2025 · PMID 40273177 · DOI 10.1371/journal.pone.0321808
Verify or expand the search:
- PubMed search for NCT06736925
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06736925 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Indiana University
- Last refreshed: 5 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06736925.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing