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NCT06726525
Hydroxypropyl-methylcellulose and GlicoPro® Eyedrops in the Treatment of Dry Eye Disease: Clinical Study
Phase 4 trial testing HPMC+GlicoPro eyedrops in Dry Eye in 44 participants. Completed in 12 September 2024.
12 September 2024
Quick facts
| Lead sponsor | University of Milan |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 44 |
| Start date | 3 February 2024 |
| Primary completion | 12 September 2024 |
| Estimated completion | 12 September 2024 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- HPMC+GlicoPro eyedrops
- Hydroxypropyl-methylcellulose
Conditions studied
- Dry Eye — all drugs for Dry Eye →
Sponsor
University of Milan
Who can join
18 and older, any sex, with Dry Eye. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to learn if Hydroxypropyl-methylcellulose and GlicoPro® eyedrops work to treat mild-to-moderate dry eye disease in adult patients. The main questions it aims to answer are: Do Hydroxypropyl-methylcellulose and GlicoPro® eyedrops reduce patients' symptoms? Do Hydroxypropyl-methylcellulose and GlicoPro® eyedrops increase patients' tear film stability? Researchers will compare Hydroxypropyl-methylcellulose and GlicoPro® eyedrops to Hydroxypropyl-methylcellulose without GlicoPro® eyedrops to see if Hydroxypropyl-methylcellulose and GlicoPro® formulation works better to treat dry eye.. Participants will * Take Hydroxypropyl-methylcellulose and GlicoPro® eyedrops or Hydroxypropyl-methylcellulose eyedrops every day for 3 months * Visit the clinic 3 times in 3 months for checkups and tests
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Hydroxypropyl-Methylcellulose and GlicoPro<sup>®</sup> Eyedrops in the Treatment of Dry Eye Disease: In Vitro and Clinical Study.
Villani E, Campagna G, Gentili V, Postorino EI, et al · · 2025 · cited 1× · PMID 40024993 · DOI 10.1007/s40123-025-01101-6
Verify or expand the search:
- PubMed search for NCT06726525
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06726525 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Milan
- Last refreshed: 10 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06726525.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing