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NCT06713044: QRCM
Effect of Quranic Recitation and Classical Music on Pain Intensity and Interleukin-6 Levels After Lower Limb Orthopedic Surgery With Intrathecal Anesthesia
NA trial testing Murottal Therapy Intervention Name: Murottal (Islamic verse recitation) in Pain in 33 participants. Currently enrolling.
30 January 2025
Quick facts
| Lead sponsor | Universitas Jenderal Soedirman |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 33 |
| Start date | 1 September 2024 |
| Primary completion | 30 January 2025 |
| Estimated completion | 30 March 2025 |
| Sites | 1 location across Indonesia |
Drugs / interventions tested
- Murottal Therapy Intervention Name: Murottal (Islamic verse recitation)
- Classical Music Therapy Intervention Name: Classical Music Listening
- Standard Care (in control arm) — full drug profile →
Conditions studied
- Pain — all drugs for Pain →
- Pain, Postoperative — all drugs for Pain, Postoperative →
- Inflammation — all drugs for Inflammation →
- Orthopedic Surgical Procedures — all drugs for Orthopedic Surgical Procedures →
Sponsor
Universitas Jenderal Soedirman — full company profile →
Who can join
Adults 18 to 60, any sex, with Pain or Pain, Postoperative. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this study is to determine the effect of murottal and classical music on postoperative pain intensity and interleukin 6 levels in patients undergoing lower extremity orthopedic surgery with spinal anesthesia. This study also aims to evaluate whether these therapies can help reduce pain and influence the body's inflammatory response. Main questions to be answered: Can murottal or classical music reduce postoperative pain intensity in patients? Can the use of murottal or classical music lower the levels of interleukin 6, an inflammatory marker, in patients after lower extremity orthopedic surgery? Participants will: Listen to murottal or classical music during their lower extremity orthopedic surgery with spinal anesthesia. Measure pain intensity and interleukin 6 levels before and after the intervention to assess the effect of the therapy. Undergo routine checkups to ensure the safety and success of the therapy. This study aims to provide a deeper understanding of the use of non-pharmacological therapies such as murottal and classical music in managing pain and the inflammatory response in patients after orthopedic surgery.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Murottal and Classical Music Effect on Pain: Clinical Trial.
Prihatno MMR, Perkasa G, Prihartini H, Suryani S, et al · · 2025 · PMID 41229901 · DOI 10.2147/jpr.s542508
Verify or expand the search:
- PubMed search for NCT06713044
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Universitas Jenderal Soedirman trials
Trials by the same sponsor.
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- NCT06604598 — The Effect of NSAID Steroid Therapy for PGE2 Level and Analgesia After Percutaneous Nephrolithotomy Surgery · Phase 4 · completed
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06713044 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universitas Jenderal Soedirman
- Last refreshed: 3 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06713044.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing