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NCT06698419
RADA16 on Mastoid Cavity Epithelialization
NA trial testing RADA16 gel application into mastoid cavity in Delayed Wound Healing in 14 participants. Not yet recruiting.
1 January 2026
Quick facts
| Lead sponsor | University of Florida |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 14 |
| Start date | 1 January 2025 |
| Primary completion | 1 January 2026 |
| Estimated completion | 1 January 2027 |
Drugs / interventions tested
- RADA16 gel application into mastoid cavity
Conditions studied
- Delayed Wound Healing — all drugs for Delayed Wound Healing →
Sponsor
University of Florida
Who can join
18 and older, any sex, with Delayed Wound Healing. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to see if the application of RADA16 gel can expedite and improve the healing process in participants after canal wall down mastoidectomy. The main questions are: * Does application of RADA16 in the mastoid cavity after canal wall down mastoidectomy lead to faster healing (i.e. epithelialization)? * Is application of RADA16 in the mastoid cavity after canal wall down mastoidectomy associated with a decreased need for medications after surgery (i.e. antibiotics, steroids), less frequent in-office debridements, and less postoperative appointments? Researchers will compare the healing outcomes in participants treated with RADA16 gel to those in a control group who do not receive the treatment. Participants will: * Undergo canal wall down mastoidectomy as recommended regardless of participation in the clinical trial * Follow-up postoperatively for clinical assessment at 1 month, 2 months, 3 months, 6 months, 1 year, 18 months, and 2 years. Participants may follow-up more frequently as needed.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06698419
- Europe PMC full search
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06698419 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Florida
- Last refreshed: 21 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06698419.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing