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NCT06682078: DEV-GEN-RiTuGo

Disorders of Sexual Development and Gonadal Tumor Risk

Completed Last updated 13 April 2025
What this trial tests

trial testing Not applicable . Non-interventional retrospective study, only on datas. in Disorders of Sexual Development in 80 participants. Completed in 1 June 2024.

Timeline
1 September 2023
Primary endpoint
1 December 2023
1 June 2024

Quick facts

Lead sponsorHospices Civils de Lyon
StatusCompleted
Study typeOBSERVATIONAL
Enrollment80
Start date1 September 2023
Primary completion1 December 2023
Estimated completion1 June 2024
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

Hospices Civils de Lyon — full company profile →

Who can join

Eligibility, any sex, with Disorders of Sexual Development. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Disorders of Sexual Development are rare and represent a spectrum of heterogeneous pathologies. The risk of developing a malignant gonadal germ cell tumor (MGCT) exists and varies according to the etiology. The indication for prophylactic gonadectomy must be modulated and discussed for all patients. It is essential to assess each patient's individual risk. The aim of our study is to assess gonadal tumor risk in patients with Disorders of Sexual Development according to etiology The primary objective is to evaluate tumor risk and the indication for gonadectomy in cases of Disorders of Sexual Development according to etiology. The secondary objectives are to evaluate the timing of gonadectomy, to monitor changes in practice over time, and to assess the contribution of imaging and/or biological tests to tumor detection.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other Hospices Civils de Lyon trials

Trials by the same sponsor.

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Data sources for this page

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing