NCT06671613 (Stage IV NSCLC) is a NA clinical trial of FMD in Stage IV NSCLC, sponsored by VA Office of Research and Development.

Who is sponsoring NCT06671613?

NCT06671613 is sponsored by VA Office of Research and Development.

What drugs are being tested in NCT06671613?

Interventions in NCT06671613: FMD, Regular Diet Plus FMD.

What condition does NCT06671613 study?

NCT06671613 studies Stage IV NSCLC, NSCLC, Immunotherapy, Fasting Mimicking Diet.

Is NCT06671613 still recruiting?

NCT06671613 is currently recruiting now. Last updated 10 November 2025.

Last reviewed 2025-11-10 · How we verify

NCT06671613: Stage IV NSCLC

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluating a Fasting-mimicking Diet in Combination With Immunotherapy in Patients With Non-small Cell Lung Cancer

Recruiting now NA Last updated 10 November 2025

What this trial tests

NA trial testing FMD in Stage IV NSCLC in 66 participants. Currently enrolling.

Timeline

27 October 2025

Primary endpoint
31 December 2029

31 December 2030

Quick facts

Lead sponsor	VA Office of Research and Development
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	supportive care
Enrollment	66
Start date	27 October 2025
Primary completion	31 December 2029
Estimated completion	31 December 2030
Sites	4 locations across United States

Drugs / interventions tested

FMD
Regular Diet Plus FMD

Conditions studied

Stage IV NSCLC — all drugs for Stage IV NSCLC →
NSCLC — all drugs for NSCLC →
Immunotherapy — all drugs for Immunotherapy →
Fasting Mimicking Diet — all drugs for Fasting Mimicking Diet →

Sponsor

VA Office of Research and Development — full company profile →

Who can join

18 and older, any sex, with Stage IV NSCLC or NSCLC. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to learn the effects of fasting on cancer cells while you get maintenance treatment.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Gut microbiota shapes cancer immunotherapy responses.
Lei W, Zhou K, Lei Y, Li Q, et al · · 2025 · cited 33× · PMID 40715107 · DOI 10.1038/s41522-025-00786-8
Gut microbiome changes and cancer immunotherapy outcomes associated with dietary interventions: a systematic review of preclinical and clinical evidence.
Somodi C, Dora D, Horváth M, Szegvari G, et al · · 2025 · cited 7× · PMID 40629403 · DOI 10.1186/s12967-025-06586-0
Nutritional strategies in supporting immune checkpoint inhibitor, PI3K inhibitor, and tyrosine kinase inhibitor cancer therapies.
Fuller-Shavel N, Davies EJ, Peleg Hasson S. · · 2025 · PMID 41425618 · DOI 10.3389/fnut.2025.1670598

Verify or expand the search:

Other trials of FMD

Trials testing the same drug.

NCT05125913 — Long Term Cardio-Vascular Risk Assessment in CKD and Kidney Transplanted Patients Following SARS-COV-2 · unknown
NCT04409847 — COVID-19 Blood Pressure Endothelium Interaction Study (OBELIX) · completed
NCT04027478 — Can Fasting Decrease the Side Effects of Chemotherapy? · NA · unknown
NCT04029571 — Effect and Safety of TCM-FMD in Phlegm-Dampness Type Overweight/Obesity Patients(EASTAR) · Phase 2 · completed
NCT03454282 — Impact of Dietary Intervention on Tumor Immunity: the DigesT Trial · NA · unknown

Other VA Office of Research and Development trials

Trials by the same sponsor.

NCT07456150 — Personalizing Veteran Pain Care: Adapting Coaching Interventions to Support Maintenance of Self-Care · Phase 1 · not yet recruiting
NCT06746727 — The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among Veteran · NA · not yet recruiting
NCT07362576 — Perinatal Peer Support for Veterans With Serious Mental Illness · NA · not yet recruiting
NCT06766331 — Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans · NA · not yet recruiting
NCT07397195 — ACT for Veterans With IBD and Mental Health Challenges · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06671613 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by VA Office of Research and Development
Last refreshed: 10 November 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06671613.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing