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NCT06668831: FibCA-HD

Fibroblast Growth Factor 23 and Risk of Cardiac Arrhythmias in Hemodialysis Patients

Recruiting now Last updated 5 August 2025
What this trial tests

trial in Hemodialysis in 30 participants. Currently enrolling.

Timeline
12 October 2024
Primary endpoint
31 October 2025
30 December 2025

Quick facts

Lead sponsorAntonio Bellasi
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment30
Start date12 October 2024
Primary completion31 October 2025
Estimated completion30 December 2025
Sites1 location across Switzerland

Conditions studied

Sponsor

Antonio Bellasi

Who can join

18 and older, any sex, with Hemodialysis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Despite recent progress in the field of hemodialysis (HD), mortality remains unacceptably high, particularly due to cardiac arrhythmias. Recent evidence suggests that fibroblast growth factor 23 (FGF23) is implicated in the pathogenesis of cardiac arrhythmias and sudden death. However, several aspects of both the pathogenetic mechanism(s) as well as the actual association in individuals with Chronic Kidney Disease (CKD) and the effect of dialysis clearance of FGF23 need to be elucidated. The investigators aim at testing the independent association of FGF23 changes due to dialysis removal and electrocardiographic (ECG) abnormalities (namely QTc prolongation) in a well characterized sample of patients undergoing maintenance HD. The study will be developed in the Division of Nephrology, Ente Ospedaliero Cantonale.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06668831.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing