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NCT06665841: SeHPV
Correlation Between Selenium Levels in Human Tissues and HPV-related Cervical Lesions and Outcomes
trial in Cervical Intraepithelial Neoplasia (CIN) in 200 participants. Not yet recruiting.
30 June 2027
Quick facts
| Lead sponsor | Second Affiliated Hospital of Wenzhou Medical University |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 200 |
| Start date | 1 November 2024 |
| Primary completion | 30 June 2027 |
| Estimated completion | 31 December 2027 |
Conditions studied
- Cervical Intraepithelial Neoplasia (CIN) — all drugs for Cervical Intraepithelial Neoplasia (CIN) →
- Cervical Cancer — all drugs for Cervical Cancer →
- Persistent HPV Infection — all drugs for Persistent HPV Infection →
Sponsor
Second Affiliated Hospital of Wenzhou Medical University
Who can join
Adults 18 to 65, female only, with Cervical Intraepithelial Neoplasia (CIN) or Cervical Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study investigates the relationship between selenium levels in human tissues and the persistence of HPV (human papillomavirus) infection, particularly focusing on cervical-related lesions. The main objectives are to explore the correlation between selenium levels in different body samples (hair, nails, urine, and blood) and to evaluate selenium's potential protective effects against HPV persistence and its progression to cervical lesions. Key goals of the study include: Determining whether non-invasive monitoring (e.g., hair, nails, urine) can accurately reflect blood selenium levels. Understanding how selenium levels fluctuate in women with persistent HPV infection, and whether selenium supplementation can reduce the risk of HPV-related cervical disease progression. Exploring selenium's role in enhancing immune function, especially in older adults, to help clear HPV infection. By recruiting volunteers for selenium level testing and tracking HPV-positive women over time, this research aims to provide evidence on the effectiveness of selenium in preventing cervical cancer progression and potentially clearing HPV infections.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06665841
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06665841 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Second Affiliated Hospital of Wenzhou Medical University
- Last refreshed: 30 October 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06665841.
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