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NCT06653894: PENG vs QLB
Postoperative Analgesic Efficacy of PENG and QLB Blocks in Hip Surgeries
NA trial testing PENG block with 0.25% bupivacaine. in Hip Surgery in 73 participants. Completed in 3 April 2025.
1 April 2025
Quick facts
| Lead sponsor | Gaziosmanpasa Research and Education Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 73 |
| Start date | 25 October 2024 |
| Primary completion | 1 April 2025 |
| Estimated completion | 3 April 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- PENG block with 0.25% bupivacaine. — full drug profile →
- anterior quadratus lumborum block
Conditions studied
- Hip Surgery — all drugs for Hip Surgery →
- Postoperative Analgesia — all drugs for Postoperative Analgesia →
Sponsor
Gaziosmanpasa Research and Education Hospital
Who can join
40 and older, any sex, with Hip Surgery or Postoperative Analgesia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This prospective, randomized, single-blinded study compares the postoperative analgesic efficacy of the Pericapsular Nerve Group (PENG) block and Quadratus Lumborum Block (QLB) in hip surgeries under spinal anesthesia. the study focuses on time to first rescue analgesia and total analgesic consumption within the first 48 hours postoperatively in patients over 40 years undergoing elective hip surgery. Ninety patients will be randomized into two groups (PENG or QLB) using a sealed envelope method. The study will assess pain scores, opioid consumption, and side effects, hypothesizing that both blocks provide effective analgesia but seek to identify which offers superior efficacy. Statistical analysis will be performed with SPSS, aiming to contribute valuable insights into analgesic techniques for hip surgeries.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Comparison of the postoperative analgesic efficacy of pericapsular nerve group block (PENG) and anterior quadratus lumborum block in hip fracture surgery: A prospective randomized study.
Şehirlioğlu S, Moralar DG. · · 2025 · PMID 41032577 · DOI 10.1177/00368504251382032
Verify or expand the search:
- PubMed search for NCT06653894
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of PENG block with 0.25% bupivacaine.
Trials testing the same drug.
- NCT06166602 — US-guided Pericapsular Nerve Group (PENG) Block in Different Volumes on Postoperative Pain in Hip Replacement Surgeries · NA · completed
Other recruiting trials for Hip Surgery
Currently open trials in the same condition.
- NCT07513740 — PENG vs Deep Iliacus Plane Block in Intertrochanteric Femur Fractures · NA · recruiting
- NCT07017192 — OPPOSED (anteriOr hiP arthroPlasty regiOnal aneSthEsia stuDy) Study · NA · recruiting
- NCT07147491 — Effectiveness and Safety of the Electrically Powered Orthopedic Exercise Device on Gait Ability in Patients With Who Hav · Phase 4 · recruiting
- NCT06093477 — Studying Melatonin and Recovery in Teens · NA · recruiting
Other Gaziosmanpasa Research and Education Hospital trials
Trials by the same sponsor.
- NCT07459400 — The Effect of Peloidotherapy in Young Adults Undergoing Physical Therapy Scoliosis Specific Exercises (PSSE) · not yet recruiting
- NCT07366814 — Pipelle Versus Karman Endometrial Biopsy Under Standardized Paracervical Block · NA · completed
- NCT07372430 — Proximal Versus Distal Superior Cluneal Nerve Block in Entrapment Neuropathy · recruiting
- NCT07459413 — Oral vs. Intravenous Hydration to Prevent Contrast-Associated Acute Kidney Injury in the ED · NA · recruiting
- NCT07272213 — Thyroid-Stimulating Hormone Levels in Pregnancy and Their Association With Depression, Anxiety, and Sexual Function · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06653894 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Gaziosmanpasa Research and Education Hospital
- Last refreshed: 7 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06653894.
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