Last reviewed · How we verify
NCT07459400
The Effect of Peloidotherapy in Young Adults Undergoing Physical Therapy Scoliosis Specific Exercises (PSSE)
trial testing Adult Scoliosis Study Form in Spine Deformity in 54 participants. Not yet recruiting.
25 September 2026
Quick facts
| Lead sponsor | Gaziosmanpasa Research and Education Hospital |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 54 |
| Start date | 23 February 2026 |
| Primary completion | 25 September 2026 |
| Estimated completion | 23 October 2026 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Adult Scoliosis Study Form
- Scoliosis graphy
- Visuel Aanalog Scale
- Adam's Test
- TRACE (Trunk Aesthetic Clinical Evaluation)
Conditions studied
- Spine Deformity — all drugs for Spine Deformity →
- Adult Scoliosis — all drugs for Adult Scoliosis →
- Peloidotherapy — all drugs for Peloidotherapy →
Sponsor
Gaziosmanpasa Research and Education Hospital
Who can join
Adults 20 to 40, any sex, with Spine Deformity or Adult Scoliosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Scoliosis is a musculoskeletal disorder defined by a three-dimensional spinal deformity that can result in substantial clinical and functional limitations, particularly during adolescence and young adulthood. Affected individuals commonly experience postural asymmetry, muscular imbalance, pain, and diminished quality of life. In conservative management, Physiotherapeutic Scoliosis-Specific Exercises (PSSE) have gained recognition as a fundamental intervention. The primary objectives of PSSE include optimizing spinal alignment, facilitating rotational breathing, and restoring muscular symmetry to improve functional capacity. Evidence from systematic reviews suggests that PSSE, especially the Schroth method, are superior to general exercise programs in improving both radiographic parameters and health-related quality of life.Meta-analytic findings further support the effectiveness of PSSE in reducing curve magnitude and enhancing quality of life outcomes. Among the various PSSE approaches, the Schroth method is one of the most extensively investigated and widely applied in clinical settings. This method incorporates three-dimensional postural correction, targeted breathing techniques, and the development of postural awareness. Randomized controlled trials have demonstrated that Schroth exercises significantly improve SRS-22 quality of life scores and positively influence pain, body image, and overall well-being.Despite these established benefits, pain and muscle tension occurring during exercise sessions may negatively influence adherence to rehabilitation programs. In young adults, pain is a critical factor limiting treatment compliance and restricting engagement in daily activities. Accordingly, adjunctive interventions implemented prior to exercise may enhance exercise tolerance and optimize therapeutic outcomes.Peloidotherapy, which involves the therapeutic application of natural medicinal mud, is commonly used in musculoskeletal rehabilitation due to its analgesic, muscle-relaxant, and circulation-enhancing effects. By alleviating pain and reducing muscular tension, peloidotherapy may facilitate greater participation in exercise programs and support improved clinical outcomes.This study aims to investigate the effects of adjunctive peloidotherapy administered before Schroth-based PSSE in young adults with scoliosis, focusing on pain, exercise adherence, and quality of life, with particular emphasis on SRS-22 measures..
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07459400
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Spine Deformity
Currently open trials in the same condition.
- NCT07261358 — The Effect of Three-Dimensional Exercises ( Schroth Method ) on Trunk Muscle Endurance, Sleep Quality, and Quality of Li · NA · recruiting
- NCT06815861 — Perioperative Morbidity in Adult Scoliotic Surgery: Analysis of a Series From Brest (MOSCA-B) · active not recruiting
- NCT05276024 — Evaluation of the IFuse Bedrock Technique in Association with Posterior Lumbosacral Fusion with Iliac Fixation. · recruiting
- NCT05154825 — Evaluating and Establishing the Relationship in the Five Critical X-ray Time Points in Spinal Deformity Realignment · recruiting
- NCT05038527 — ABM/P-15 Bone Graft vs Traditional Bone Graft in Adult Spinal Deformity Surgery · NA · recruiting
Other Gaziosmanpasa Research and Education Hospital trials
Trials by the same sponsor.
- NCT07366814 — Pipelle Versus Karman Endometrial Biopsy Under Standardized Paracervical Block · NA · completed
- NCT07372430 — Proximal Versus Distal Superior Cluneal Nerve Block in Entrapment Neuropathy · recruiting
- NCT07459413 — Oral vs. Intravenous Hydration to Prevent Contrast-Associated Acute Kidney Injury in the ED · NA · recruiting
- NCT07272213 — Thyroid-Stimulating Hormone Levels in Pregnancy and Their Association With Depression, Anxiety, and Sexual Function · recruiting
- NCT07163442 — Bioidentical Hormone Replacement Therapy in Postmenopausal Women · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07459400 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Gaziosmanpasa Research and Education Hospital
- Last refreshed: 9 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07459400.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing