Last reviewed · How we verify
NCT06645756: CAPE
Comparative Analysis of Postprandial Effects in Healthy and Obese Individuals
NA trial testing Test meal in Obesity in 38 participants. Completed in 6 November 2024.
6 November 2024
Quick facts
| Lead sponsor | University of Hohenheim |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 38 |
| Start date | 13 December 2023 |
| Primary completion | 6 November 2024 |
| Estimated completion | 6 November 2024 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Test meal — full drug profile →
Conditions studied
- Obesity — all drugs for Obesity →
- Normal Weigth — all drugs for Normal Weigth →
Sponsor
University of Hohenheim
Who can join
25 and older, any sex, with Obesity or Normal Weigth. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
After eating, blood composition changes, including increased triglycerides and glucose, which can trigger postprandial inflammation. Particularly with high-fat foods, pro-inflammatory lipopolysaccharide (LPS) increases. This activates leukocytes to release pro-inflammatory cytokines. In industrialized countries where "snacking" is common, many people spend the day in a postprandial state. Obese individuals tend to have chronic inflammation and show increased susceptibility to infections such as SARS-CoV-2. The main objective of the study is to investigate the response of leukocytes and the serum metabolome after food intake in individuals with obesity compared to healthy individuals, focusing on LPS as a key stimulus of innate immunity.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06645756
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Test meal
Trials testing the same drug.
- NCT06848933 — Could the Advanced Hybrid Closed-Loop System Algorithm Provide Postprandial Normoglycemia After a High-Fat, High-Protein · NA · completed
- NCT05207020 — Development and Validation of the Blood Glucose Measurement Device by Air Analysis Expired · NA · completed
- NCT04851327 — Satiation Study With Children Attending a Tertiary Feeding Clinic · NA · completed
- NCT03899974 — Metabolic Effects of High-amylose Wheat-based Breads · NA · completed
- NCT03195062 — Fructose Extra-splanchnic Metabolism and Its Effects on Systemic Flux of Substrates (FruPP) · NA · completed
Other recruiting trials for Obesity
Currently open trials in the same condition.
- NCT07403604 — Effect of Insulin Lowering on Lipogenesis · Phase 1 · recruiting
- NCT07509307 — AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee · Phase 3 · recruiting
- NCT07272837 — Impact of Semaglutide (Ozempic/Wegovy®) on Heart and Muscle Mass · recruiting
- NCT07481630 — A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoart · Phase 3 · recruiting
- NCT07527195 — Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscl · Phase 1 · recruiting
Other University of Hohenheim trials
Trials by the same sponsor.
- NCT07397962 — Treatment of Histamine Intolerance Using Probiotic Intervention · NA · completed
- NCT06450808 — The Microalga Phaeodactylum Tricornutum a Potential Fish Substitute?- Pharmacokinetic Study · NA · active not recruiting
- NCT05857345 — Breastmilk as a Source of Lactocytes · completed
- NCT05777356 — Sanitary Napkins for Urinary Assessment of Micronutrients · completed
- NCT04667208 — Biomarkers for Intestinal Permeability · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06645756 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Hohenheim
- Last refreshed: 6 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06645756.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing