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NCT06643520
19G FNB Needle vs 22G FNB Needle for EUS-Guided Liver Biopsy
NA trial testing 19-gauge in Endoscopic Ultrasonography in 82 participants. Completed in 1 April 2025.
1 March 2025
Quick facts
| Lead sponsor | Duzce University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | diagnostic |
| Enrollment | 82 |
| Start date | 1 July 2024 |
| Primary completion | 1 March 2025 |
| Estimated completion | 1 April 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- 19-gauge
- 22-gauge
Conditions studied
- Endoscopic Ultrasonography — all drugs for Endoscopic Ultrasonography →
- Liver Biopsy — all drugs for Liver Biopsy →
Sponsor
Duzce University
Who can join
Adults 18 to 80, any sex, with Endoscopic Ultrasonography or Liver Biopsy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
EUS-guided liver biopsy (EUS-LB) is increasingly used to diagnose patients with liver disease, especially in anxious patients who need sedation. There is an ongoing debate about the optimal needle size for EUS-LB. Some clinicians prefer a thinner 22-gauge biopsy needle because they presume it to be safer, and some studies show that their performance is the same as a thicker 19-gauge needle. However, some other studies show that the adequacy and diagnostic accuracy of a 19-gauge needle is better, and the rates of adverse events are the same. In this study, we aimed to compare the adequacy and diagnostic accuracy of samples obtained by the same endoscopist from the same liver lobe during the same session.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06643520
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06643520 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Duzce University
- Last refreshed: 5 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06643520.
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