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NCT07163468: NEURO-ACL
Neuromusculoskeletal Alterations After ACL Injury
trial in Anterior Cruciate Ligament Injuries in 60 participants. Completed in 1 August 2025.
15 July 2025
Quick facts
| Lead sponsor | Duzce University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 60 |
| Start date | 1 June 2025 |
| Primary completion | 15 July 2025 |
| Estimated completion | 1 August 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Conditions studied
- Anterior Cruciate Ligament Injuries — all drugs for Anterior Cruciate Ligament Injuries →
- Sports Injury — all drugs for Sports Injury →
- Neurocognitive Function — all drugs for Neurocognitive Function →
Sponsor
Duzce University
Who can join
Adults 18 to 30, male only, with Anterior Cruciate Ligament Injuries or Sports Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study investigated how anterior cruciate ligament (ACL) injuries affect not only the knee joint but also brain activity, reaction speed, and psychological readiness to return to sports. A total of 60 male athletes, aged 18 to 30 years, were evaluated in three groups: healthy athletes, athletes who had undergone primary ACL reconstruction, and athletes who had undergone revision ACL reconstruction. The study measured brain activity with electroencephalography (EEG), reaction time with a computer-based test, and psychological status with standardized questionnaires. The findings showed that athletes with revision ACL surgery had more difficulties in attention control, slower reaction times, and greater psychological barriers compared to the other groups. These results suggest that ACL injuries and surgeries may influence not only physical recovery but also brain function and psychological readiness. The study highlights the importance of considering neuromuscular, cognitive, and emotional aspects when planning rehabilitation and return-to-sport decisions.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Neuromusculoskeletal alterations after ACL reconstruction: a cross-sectional study of cortical activity, motor response, and psychological readiness.
Kaya HB, Karaduman ZO, Akpınar S, Arıcan M, et al · · 2025 · PMID 41318585 · DOI 10.1186/s13102-025-01450-6
Verify or expand the search:
- PubMed search for NCT07163468
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Anterior Cruciate Ligament Injuries
Currently open trials in the same condition.
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- NCT07333092 — Investigation of the Effects of Proprioceptive Exercises After Anterior Cruciate Ligament Surgery · NA · recruiting
- NCT07346326 — Comparative Study of Functional Outcomes Between Peroneus Longus and Hamstring Tendon Autografts in Arthroscopic ACL Rec · NA · recruiting
- NCT07306221 — Effect of Visual-Guided Balance Training on Knee Motor Function and Biomechanical Characteristics After ACL Reconstructi · NA · recruiting
- NCT07486466 — ACL Mechanical Property Changes in Female Collegiate Basketball Players During a Competitive Season · active not recruiting
Other Duzce University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07163468 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Duzce University
- Last refreshed: 15 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07163468.
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