NCT06640894: Power2Walk

Power2Walk: The Impact of Functional Power Training on Participation and Activity in Children With Cerebral Palsy.

Recruiting now NA Last updated 29 December 2025

What this trial tests

NA trial testing MegaPower training in Cerebral Palsy, Spastic in 66 participants. Currently enrolling.

Timeline

19 July 2024

Primary endpoint
31 August 2027

31 August 2027

Quick facts

Lead sponsor	Amsterdam UMC, location VUmc
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	66
Start date	19 July 2024
Primary completion	31 August 2027
Estimated completion	31 August 2027
Sites	10 locations across Netherlands

Drugs / interventions tested

• MegaPower training
• Usual Care

Conditions studied

• Cerebral Palsy, Spastic — all drugs for Cerebral Palsy, Spastic →

Sponsor

Amsterdam UMC, location VUmc — full company profile →

Who can join

Adults 4 to 12, any sex, with Cerebral Palsy, Spastic. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Rationale: Children with cerebral palsy (CP) experience limitations in walking ability due to functional motor impairments caused by neurodevelopmental damage during fetal or early child development. Due to these motor impairments, children with CP struggle to keep up with typically developing peers when participating in physical and/or social activities. Consequently, the development of these children may be hampered. Recently, functional power training (FPT) emerged as a potentially successful supplementary treatment method to improve participation in children with CP. It is understood that FPT is more effective than progressive resistance training in improving walking ability and endurance, and thereby better supports participation in ambulatory children with CP. Nevertheless, high-level scientific evidence underpinning the efficacy of FPT on these parameters in ambulant children with CP is still lacking. The investigators hypothesize that FPT effectively helps accomplish patient-tailored participation and activity goals in ambulant children with CP.

Objective: This study aims to investigate whether twelve weeks of FPT (MegaPower training) effectively accomplish patient-tailored participation and activity goals in ambulant children with CP, when compared to their usual care. Additionally, the goal is to investigate i) whether MegaPower training improves walking ability, aerobic endurance, and anaerobic capacity; ii) what factors best identify which ambulant children with CP benefit most from twelve weeks of MegaPower training; iii) to what extend the MegaPower training was implemented as intended in the participating study centers?, and iv) whether the effects of the MegaPower training are maintained after 12 and 24 weeks of follow-up.

Study design: A single-blind randomized controlled parallel trial with a 24 week follow-up. During the follow-up, the control group will also receive MegaPower training.

Study population: Ambulant children with cerebral palsy or a related non-progressive disorder between the ages of 4 - 12.

Intervention: One group will receive twelve weeks of FPT (MegaPower training), whilst the other group will receive twelve weeks of usual care (control group).

Main study parameters/endpoints: Accomplishment of patient-tailored participation and activity goals, measured through Goal Attainment Scaling.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.