Last reviewed · How we verify
NCT06635291: IDeAl DesiRE
Improving the Diagnostic Accuracy of Children with DoC (IDeAl DesiRE)
trial in Acquired Brain Injury in 113 participants. Currently enrolling.
31 December 2025
Quick facts
| Lead sponsor | IRCCS Eugenio Medea |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 113 |
| Start date | 20 May 2024 |
| Primary completion | 31 December 2025 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across Italy |
Conditions studied
- Acquired Brain Injury — all drugs for Acquired Brain Injury →
- Disorder of Consciousness — all drugs for Disorder of Consciousness →
Sponsor
IRCCS Eugenio Medea — full company profile →
Who can join
Adults 2 Months to 25, any sex, with Acquired Brain Injury or Disorder of Consciousness. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The present study aims to investigate the clinical evolution of children with severe ABI and DoC both by using the traditional behavioral scales, namely the CRS-R, CRS-P and CNCS, and by trying to establish whether it is possible to identify any clinical markers of Emergency (E-Markers). E-Markers are behaviors that indicate a content of consciousness irrespective of the processes investigated by behavioral scales, thus they could be combined with the items of these scales to improve the diagnosis. A particular focus will be given to the identification of specific E-Markers for children aged less than 12 months, for which the CRS-P scale cannot be used. In this case, the E-markers will be compared with the specific developmental stages of newborns, giving great importance to motor abilities.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06635291
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Acquired Brain Injury
Currently open trials in the same condition.
- NCT07378592 — Driving Simulator Training For Adults With Acquired Brain Injuries · NA · recruiting
- NCT07435155 — ACURES: Acoustic and Respiratory Parameters for Dysarthria Assessment · recruiting
- NCT07237386 — Comparing the Ceriter Stride One, a Pressure-sensitive Smart Insole, With Gait Parameters Measured on the GRAIL in Neuro · NA · recruiting
- NCT06848140 — Using Non-invasive Brain Stimulation to Treat Word Finding Difficulty in Chronic Traumatic Brain Injury · NA · recruiting
- NCT07122752 — Feasibility and Outcomes of 3D-printed External Cranial Orthosis After Craniectomy · active not recruiting
Other IRCCS Eugenio Medea trials
Trials by the same sponsor.
- NCT07095062 — Electroencephalogram in Patients With Friedreich's Ataxia for the Study of the Structural and Functional Connectome. · NA · recruiting
- NCT06993389 — AI-based Model for Rehabilitation Engagement and Motor Performance Evaluation in Pediatric Patients · recruiting
- NCT06999850 — Implementation and Validation of Instrumented Stair Climb Test · NA · recruiting
- NCT06666777 — Speech Therapy and Parenting for Early Socio-communicAtive sKills · NA · recruiting
- NCT07470138 — Sleep Disturbance in Subjects With Autism Spectrum Disorders (ASD) in Preschool Age (18-60 Months) · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06635291 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by IRCCS Eugenio Medea
- Last refreshed: 16 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06635291.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing