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NCT07470138

Sleep Disturbance in Subjects With Autism Spectrum Disorders (ASD) in Preschool Age (18-60 Months)

Recruiting now Last updated 24 March 2026
What this trial tests

trial testing follow up in Autism Spectrum Disorder in 200 participants. Currently enrolling.

Timeline
8 January 2025
Primary endpoint
15 December 2026
15 December 2026

Quick facts

Lead sponsorIRCCS Eugenio Medea
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment200
Start date8 January 2025
Primary completion15 December 2026
Estimated completion15 December 2026
Sites2 locations across Italy

Drugs / interventions tested

Conditions studied

Sponsor

IRCCS Eugenio Medea — full company profile →

Who can join

Adults 18 Months to 60 Months, any sex, with Autism Spectrum Disorder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

An observational study is one that aims to collect data from routine clinical practice, without altering a patient's standard diagnostic and therapeutic pathway (no additional instrumental or laboratory tests beyond those performed in clinical practice are envisaged). The overall objective of this study is to investigate sleep disorders in preschool-aged children with Autism Spectrum Disorder. Sleep plays a key role in early brain development. The prevalence of sleep disorders in childhood is reported to be between 10 and 50%, with a prevalence of up to 86% in children with neurodevelopmental disorders. Over the past few decades, numerous studies have demonstrated a significant bidirectional connection between sleep problems and various areas of child development. Therefore, early identification of sleep disorders in childhood is essential for adequate treatment and prevention of negative cognitive and socioemotional impacts. Recent studies have demonstrated a hypothetical role for vitamin D and iron in regulating sleep. The objectives of the study are to describe sleep disturbances in a group of preschool-aged subjects with ASD (18-60 months), to measure blood ferritin and vitamin D levels, and to assess a possible correlation with specific subtypes of sleep disturbances. Given the impact that sleep disturbances have on various areas of children's development, secondary objectives include assessing a possible positive correlation between the severity of sleep disturbances and symptoms related to Autism Spectrum Disorder and/or other psychiatric comorbidities.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other trials of follow up

Trials testing the same drug.

Other recruiting trials for Autism Spectrum Disorder

Currently open trials in the same condition.

Other IRCCS Eugenio Medea trials

Trials by the same sponsor.

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Data sources for this page

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