NCT06601608 is a Phase 2 clinical trial of Herbal therapy in Periodontitis (Stage 3), sponsored by Ain Shams University.

Who is sponsoring NCT06601608?

NCT06601608 is sponsored by Ain Shams University.

What drugs are being tested in NCT06601608?

Interventions in NCT06601608: Herbal therapy, Placebo Drug.

What condition does NCT06601608 study?

NCT06601608 studies Periodontitis (Stage 3), Periodontal Pocket.

Is NCT06601608 still recruiting?

NCT06601608 is currently completed. Last updated 13 April 2026.

Last reviewed 2026-04-13 · How we verify

NCT06601608

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Efficacy of Locally Delivered Rosemary Extract Gel in Management of Periodontitis

Completed Phase 2 Last updated 13 April 2026

What this trial tests

Phase 2 trial testing Herbal therapy in Periodontitis (Stage 3) in 48 participants. Completed in 11 October 2025.

Timeline

20 October 2024

Primary endpoint
2 August 2025

11 October 2025

Quick facts

Lead sponsor	Ain Shams University
Phase	Phase 2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	48
Start date	20 October 2024
Primary completion	2 August 2025
Estimated completion	11 October 2025
Sites	1 location across Egypt

Drugs / interventions tested

Herbal therapy — full drug profile →
Placebo Drug — full drug profile →

Conditions studied

Periodontitis (Stage 3) — all drugs for Periodontitis (Stage 3) →
Periodontal Pocket — all drugs for Periodontal Pocket →

Sponsor

Ain Shams University

Who can join

Adults 25 to 45, any sex, with Periodontitis (Stage 3) or Periodontal Pocket. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Rosemary extract is known for its antibacterial, anti-inflammatory and anti-oxidant properties that make it a promising therapeutic aid as a local delivery drug in deep periodontal pockets in adjunct to non-surgical periodontal therapy in management of periodontitis. These properties are due to the high content of phenolic compounds such as carnosic acid, urolic acid, rosmarinic acid or chlorogenic acid. Rosemary extract was previously investigated and proved its effectiveness against periodontopathogens in-vitro. Thus, its selected for this study to be administered in a gel form to assess its efficacy in management of periodontitis.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Periodontitis (Stage 3)

Currently open trials in the same condition.

NCT06914596 — A Clinical Trial Comparing Overnight and 2x/Day for 30-minutes Use of the Emanate Perio PODS Post-SRP · NA · recruiting
NCT06687005 — Comparative Analysis of Gremlin-1, Syndecan-4 and IL-1 Beta Levels in Gingival Crevicular Fluid Among İndividuals With P · active not recruiting
NCT07523841 — Non-surgical Periodontitis Treatment With Aspirin and Omega-3 · NA · active not recruiting

Other Ain Shams University trials

Trials by the same sponsor.

NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06601608 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
Last refreshed: 13 April 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06601608.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing