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NCT06595017
Lidocaine Versus Magnesium Sulphate in Management of Myofascial Pain Dysfunction Syndrome
Phase 2 trial testing Magnesium sulphate in Myofascial Pain Dysfunction Syndrome in 75 participants. Not yet recruiting.
30 September 2025
Quick facts
| Lead sponsor | Misr University for Science and Technology |
|---|---|
| Phase | Phase 2 |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 75 |
| Start date | 1 October 2024 |
| Primary completion | 30 September 2025 |
| Estimated completion | 30 November 2025 |
Drugs / interventions tested
- Magnesium sulphate
- Lidocaine (drug) — full drug profile →
- Saline
Conditions studied
- Myofascial Pain Dysfunction Syndrome — all drugs for Myofascial Pain Dysfunction Syndrome →
Sponsor
Misr University for Science and Technology
Who can join
Adults 18 to 55, any sex, with Myofascial Pain Dysfunction Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to investigate the effectiveness of Magnesium Sulphate in the management of myofascial pain dysfunction syndrome in comparison to Lidocaine and Saline. A total of 75 patients suffering from myofascial pain dysfunction syndrome will be assigned into one of three groups, each with 25 patients. Group A: (Saline) includes patients enrolled for Saline injection into the trigger points. Group B: (Magnesium Sulphate) includes patients enrolled for Magnesium Sulphate injection into the trigger points. Group C: (Lidocaine) includes patients who will be enrolled for Lidocaine injection into the trigger points The primary outcome that will be investigated is (pain with a visual analogue score), and secondary outcomes will be (maximum mouth opening between edges of upper and lower incisors with millimeters, electrical activity with Electromyography, and quality of life assessed using the Oral Health Impact Profile questionnaire) The outcomes will be assessed pre-injection, 1month after injection, 3months after injection, and 6 months after injection
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06595017
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
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Related trials
Other trials of Magnesium sulphate
Trials testing the same drug.
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- NCT06977425 — Efficacy of Intraoperative Magnesium Sulphate vs Dexmedetomidine on Emergence Agitation in Pediatric Patients · NA · completed
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- NCT05837000 — Dexmedetomidine, Ketamine and Magnesium Sulphate in Caudal Block for Hypospadias Repair · Phase 4 · unknown
Other recruiting trials for Myofascial Pain Dysfunction Syndrome
Currently open trials in the same condition.
- NCT07413770 — Comparison of Treatment Modalities in Myofascial Pain Syndrome · NA · recruiting
- NCT07390851 — Magnesium Sulfate as an Adjuvant to Lidocaine in MPDS Trigger Point Injections Assessed by VAS and sEMG. · NA · recruiting
Other Misr University for Science and Technology trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06595017 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Misr University for Science and Technology
- Last refreshed: 19 September 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06595017.
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