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NCT06585800
Exploring the Landscape of Somatic Mutations in Human Tissue
trial testing sample collection in Somatic Mutation in 1,800 participants. Enrolling by invitation.
31 January 2026
Quick facts
| Lead sponsor | The Wellcome Sanger Institute |
|---|---|
| Status | ENROLLING BY INVITATION |
| Study type | OBSERVATIONAL |
| Enrollment | 1,800 |
| Start date | 1 March 2019 |
| Primary completion | 31 January 2026 |
| Estimated completion | 31 January 2026 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- sample collection — full drug profile →
Conditions studied
- Somatic Mutation — all drugs for Somatic Mutation →
Sponsor
The Wellcome Sanger Institute
Who can join
18 and older, any sex, with Somatic Mutation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Every cell in the human body contains a blueprint of the body called the genome. Throughout life, the genome can become damaged resulting in errors (mutations) that can change the way cells behave and may result in diseases such as cancer. Examining the mutations found the genome of both normal (non-cancerous) and diseased cells can give a valuable insight into the very earliest stages of cancer development. Comparing the number and type of mutations in different normal tissues is revealing new insights, helping us to better understand more about why cancer develops.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06585800
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other trials of sample collection
Trials testing the same drug.
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Other recruiting trials for Somatic Mutation
Currently open trials in the same condition.
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Other The Wellcome Sanger Institute trials
Trials by the same sponsor.
- NCT06832150 — SMS 2: Impact of Cancer Therapy on the Somatic Mutational Landscape of Normal Tissues · enrolling by invitation
- NCT06656767 — Somatic Mutation in Chronic Liver Disease · enrolling by invitation
- NCT06820294 — Retrospective WGS Study · enrolling by invitation
- NCT06820151 — Exploring the Landscape of Injury and Repair in the Human Oesophagus · enrolling by invitation
- NCT06584994 — Investigating the Role of Genetics in Disease Predisposition · enrolling by invitation
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06585800 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Wellcome Sanger Institute
- Last refreshed: 19 September 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06585800.
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