Last reviewed · How we verify
NCT06584461
Interest of Lidocaine in Children with Upper Airway Infection Undergoing General Anesthesia
Phase 4 trial testing Lidocaine (drug) in Upper Respiratory Tract Infections in 102 participants. Completed in 5 February 2024.
31 December 2023
Quick facts
| Lead sponsor | Tunis University |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 102 |
| Start date | 2 January 2023 |
| Primary completion | 31 December 2023 |
| Estimated completion | 5 February 2024 |
| Sites | 1 location across Tunisia |
Drugs / interventions tested
- Lidocaine (drug) — full drug profile →
- Saline (NaCl 0,9 %) (placebo) — full drug profile →
Conditions studied
- Upper Respiratory Tract Infections — all drugs for Upper Respiratory Tract Infections →
- Perioperative Respiratory Complications — all drugs for Perioperative Respiratory Complications →
Sponsor
Tunis University
Who can join
Adults 12 Months to 14, any sex, with Upper Respiratory Tract Infections or Perioperative Respiratory Complications. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to determine whether intravenous (IV) lidocaine reduces the incidence of perioperative respiratory complications (PRCs) in children with upper respiratory tract infections undergoing general anesthesia. The study will also evaluate the safety of IV lidocaine in this population. The main questions it aims to answer are: 1. Does IV lidocaine lower the incidence of perioperative respiratory complications (e.g., laryngospasm, cough, desaturation) compared to a placebo? 2. What are the side effects associated with the administration of IV lidocaine in these children? Researchers will compare IV lidocaine to a placebo to assess its effectiveness in reducing PRCs.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06584461
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Lidocaine (drug)
Trials testing the same drug.
- NCT07511400 — The Role of NaV1.8 in Human Pain Models · EARLY_PHASE1 · not yet recruiting
- NCT07430085 — Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA · Phase 4 · not yet recruiting
- NCT07359560 — Lidocaine vs Magnesium Sulfate for Hemodynamic Stability During Emergence in Infertility-Related Laparoscopic Surgery" · NA · not yet recruiting
- NCT07347977 — Lidocaine Decreases Postoperative Lung Cancer Reoccurance and Metatasis Risk · NA · not yet recruiting
- NCT07043023 — LIDOCRIT : Effect of Continuous Intravenous LIDOcaine on Discomfort in Postoperative CRITical Care Inpatients · Phase 4 · not yet recruiting
Other recruiting trials for Upper Respiratory Tract Infections
Currently open trials in the same condition.
- NCT06271655 — Rapid Diagnosis of Viral Acute Respiratory Infection to Decrease Unnecessary Antibiotic Utilization in the Emergency Dep · NA · active not recruiting
Other Tunis University trials
Trials by the same sponsor.
- NCT06655571 — What Technique for Caudal Block in Children: Conventional or Ultrasound-guided · NA · recruiting
- NCT06670846 — Management of Preoperative Anxiety in Children: Could a Lollipop Be the Solution? · NA · recruiting
- NCT06655168 — Orotracheal Intubation in Newborns: Videolaryngoscopy Vs Direct Laryngoscopy · NA · recruiting
- NCT07459088 — Central Venous Catheterization in Children: Jugulo-subclavian Venous Confluence Versus Internal Jugular Vein · NA · completed
- NCT07088432 — Intravenous Dexamethasone for Prolonging Sensory Block in Spinal Anesthesia · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06584461 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tunis University
- Last refreshed: 19 September 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06584461.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing