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NCT06562036
Efficacy of Milrinone With Sildenafil in Persistent Pulmonary Hypertension in Children
NA trial testing Sildenafil in Persistent Pulmonary Hypertension of the Newborn in 42 participants. Completed in 31 May 2024.
31 May 2024
Quick facts
| Lead sponsor | Muhammad Aamir Latif |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 42 |
| Start date | 1 December 2023 |
| Primary completion | 31 May 2024 |
| Estimated completion | 31 May 2024 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Sildenafil (sildenafil) — full drug profile →
- Milrinone (MILRINONE) — full drug profile →
Conditions studied
- Persistent Pulmonary Hypertension of the Newborn — all drugs for Persistent Pulmonary Hypertension of the Newborn →
Sponsor
Muhammad Aamir Latif — full company profile →
Who can join
Adults 1 Day to 28 Days, any sex, with Persistent Pulmonary Hypertension of the Newborn. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Neonates with persistent pulmonary hypertension (PPH) should be administered inhaled nitric oxide (iNO) and extracorporeal membrane oxygenation (ECMO), but these are not available in most resource-constrained settings like ours. This study was planned to compare the outcomes of Milrinone plus Sildenafil versus Sildenafil alone in the treatment of PPH in neonates.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06562036
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT06778330 — The Effect of Combination of Dapagliflozin and Sildenafil in Treatment of Heart Failure Patients With Secondary Pulmonar · NA · completed
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Other recruiting trials for Persistent Pulmonary Hypertension of the Newborn
Currently open trials in the same condition.
- NCT04938167 — Preductal Oxygen Saturation Target in Term and Late Preterm Neonates With Hypoxemic Respiratory Failure or Pulmonary Hyp · NA · active not recruiting
Other Muhammad Aamir Latif trials
Trials by the same sponsor.
- NCT07462182 — Impact of Enoxaparin Therapy on Fetal Outcomes in Intrauterine Growth Restriction · NA · not yet recruiting
- NCT07426744 — Antipyretic Therapy With and Without Cold Sponging · NA · not yet recruiting
- NCT07437391 — Effect of L-Carnitine Supplementation in Preterm Neonates · NA · recruiting
- NCT07313670 — Outcome of Using Hydrocortisone in Early Treatment of Pediatric Septic Shock · NA · not yet recruiting
- NCT07305935 — Comparison of Early Caffeine Administration Vs Supportive Therapy in Preventing Acute Kidney Injury · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06562036 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Muhammad Aamir Latif
- Last refreshed: 26 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06562036.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing