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NCT04938167: POST-IT
Preductal Oxygen Saturation Target in Term and Late Preterm Neonates With Hypoxemic Respiratory Failure or Pulmonary Hypertension
NA trial testing 95% - 99% SpO2 target in Persistent Pulmonary Hypertension of the Newborn in 54 participants. Participants enrolled and being followed up; not accepting new ones.
31 December 2024
Quick facts
| Lead sponsor | University of California, Davis |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 54 |
| Start date | 1 August 2021 |
| Primary completion | 31 December 2024 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- 95% - 99% SpO2 target
Conditions studied
- Persistent Pulmonary Hypertension of the Newborn — all drugs for Persistent Pulmonary Hypertension of the Newborn →
- Hypoxemic Respiratory Failure — all drugs for Hypoxemic Respiratory Failure →
Sponsor
University of California, Davis
Who can join
Adults 0 Days to 28 Days, any sex, with Persistent Pulmonary Hypertension of the Newborn or Hypoxemic Respiratory Failure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this research is to evaluate two oxygen saturation goals for newborns with pulmonary hypertension. Participation in this research will involve random assignment to one of two oxygen saturation goals, review of the medical record and targeted echocardiograms.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Factors to Consider to Study Preductal Oxygen Saturation Targets in Neonatal Pulmonary Hypertension.
Siefkes H, Sunderji S, Vaughn J, Sankaran D, et al · · 2022 · cited 3× · PMID 35327768 · DOI 10.3390/children9030396
Verify or expand the search:
- PubMed search for NCT04938167
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other University of California, Davis trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04938167 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of California, Davis
- Last refreshed: 8 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04938167.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing