NCT06558695: TIVA

Stability Comparison of TIVA and Sevoflurane in Prone Spinal Surgery(TIVA:Total Intravenous Anesthesia)

Completed NA Last updated 19 August 2024

What this trial tests

NA trial testing Sevoflurane in Spinal Stenosis, Lumbosacral Region in 52 participants. Completed in 30 June 2024.

Timeline

1 May 2023

Primary endpoint
30 June 2023

30 June 2024

Quick facts

Lead sponsor	Saglik Bilimleri Universitesi
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	screening
Enrollment	52
Start date	1 May 2023
Primary completion	30 June 2023
Estimated completion	30 June 2024
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• Sevoflurane — full drug profile →
• TIVA — full drug profile →

Conditions studied

• Spinal Stenosis, Lumbosacral Region — all drugs for Spinal Stenosis, Lumbosacral Region →

Sponsor

Saglik Bilimleri Universitesi — full company profile →

Who can join

Adults 18 to 65, any sex, with Spinal Stenosis, Lumbosacral Region. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Key Points:

1. Objective:

o To compare the effects of Total Intravenous Anesthesia (TIVA) and sevoflurane anesthesia on respiratory mechanics, hemodynamic parameters, and neuromonitoring during prone position spinal surgeries.
2. Methodology:

* A randomized controlled trial involving 52 patients scheduled for lumbar spine surgery, randomly assigned to either TIVA or sevoflurane groups.
* Respiratory and hemodynamic parameters were measured at various time points.
3. Results:

* No significant differences were found between the TIVA and sevoflurane groups in terms of respiratory mechanics or hemodynamic stability.
* Both anesthesia techniques maintained stable intraoperative conditions.
4. Clinical Implications:

* Anesthesiologists can flexibly choose between TIVA and sevoflurane based on patient-specific factors and surgical requirements.
* TIVA may be preferred in surgeries with high neurological risk due to its compatibility with neuromonitoring.
5. Future Research:

* Studies with broader patient populations and long-term outcomes are needed to further refine anesthesia management strategies.
* Research on the environmental impact and cost-effectiveness of anesthesia techniques is also important.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.