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NCT06551792
The Effect of Magnesium Deficiency on Transforaminal Epidural Steroid Injection Success: An Observational Study
trial testing Effect of Serum Magnesium Level on the Success of Transforaminal Epidural Steroid Injection in Pain, Back in 118 participants. Completed in 15 September 2024.
30 August 2024
Quick facts
| Lead sponsor | Kanuni Sultan Suleyman Training and Research Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 118 |
| Start date | 1 June 2024 |
| Primary completion | 30 August 2024 |
| Estimated completion | 15 September 2024 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Effect of Serum Magnesium Level on the Success of Transforaminal Epidural Steroid Injection
Conditions studied
- Pain, Back — all drugs for Pain, Back →
Sponsor
Kanuni Sultan Suleyman Training and Research Hospital
Who can join
Adults 18 to 65, any sex, with Pain, Back. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Transforaminal epidural steroid injection (TFESE) is an interventional method frequently used in the treatment of radicular pain due to disc herniation. TFESE, which is applied under sterile conditions and under fluoroscopy guidance, increases its effectiveness when applied in the early period (first 3 months). Inflammation and increase in neurotransmitters in the nerve root due to disc herniation trigger pain. Steroids and local anesthetics applied to the nerve root with TFESE exhibit strong anti-inflammatory effects. Factors affecting the success of TFESE include the type and dose of drugs, the age of the patient, any accompanying comorbidities, the level of injection administered and other musculoskeletal problems. Studies on the effect of these parameters on the effectiveness of TFESE are limited.Cardiac arrhythmia, muscle spasms, tetany, fasciculation paresthesia, widespread body pain, impaired bone mineralization, electrolyte disorders such as hypokalemia, hypocalcemia, hypophosphatemia, depression, and seizures may occur due to magnesium deficiency. One of the most important causes of low back pain is degenerative disc disease, and magnesium deficiency has been shown to be associated with low back pain.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06551792
- Europe PMC full search
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Related trials
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Currently open trials in the same condition.
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Other Kanuni Sultan Suleyman Training and Research Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06551792 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kanuni Sultan Suleyman Training and Research Hospital
- Last refreshed: 12 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06551792.
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