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NCT06365268: CONTRAST

Perinatal Thoraco-abdomino-pelvic Tumors Study

Completed Last updated 19 September 2025
What this trial tests

trial testing Collection of data from the patient's medical file in Perinatal Solid Tumors of the Thoraco-abdomino-pelvic Region in 152 participants. Completed in 10 October 2024.

Timeline
5 September 2024
Primary endpoint
10 October 2024
10 October 2024

Quick facts

Lead sponsorAssistance Publique - Hôpitaux de Paris
StatusCompleted
Study typeOBSERVATIONAL
Enrollment152
Start date5 September 2024
Primary completion10 October 2024
Estimated completion10 October 2024
Sites5 locations across France

Drugs / interventions tested

Conditions studied

Sponsor

Assistance Publique - Hôpitaux de Paris — full company profile →

Who can join

Under 3 Months, any sex, with Perinatal Solid Tumors of the Thoraco-abdomino-pelvic Region. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Congenital tumors are a rare diagnosis in the fetus and newborn. They differ from those of children and adults in terms of the nature, location and evolution of the tumor. Indeed, some histologically benign tumors may have lethal potential in utero (e.g. sacrococcygeal teratomas) or even undergo malignant transformation if left untreated. In contrast, other tumors that are malignant by histological criteria may have a very good prognosis, regressing spontaneously within the first year of life (e.g. neuroblastoma). Despite advances in imaging, benign and malignant solid tumors remain a major diagnostic and prognostic challenge in the antenatal context. The management of congenital tumors requires multidisciplinary expertise, taking into account the perinatal context, which poses specific problems, particularly in terms of therapeutic aspects, but also the frequent existence of associated malformations and/or genetic predisposition syndromes. This study focuses on solid tumors of the thoraco-abdomino-pelvic region, the main objective being to investigate the correlation between antenatal clinical and radiological analysis and confirmed postnatal diagnosis of congenital solid truncal tumors, as well as the developmental spectrum in which they fit.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Prenatal diagnosis and postnatal management of perinatal thoracoabdominopelvic tumors: multicenter experience.
    Khawand C, Orbach D, Berrebi D, Branchereau S, et al · · 2025 · PMID 40847681 · DOI 10.1002/uog.70000

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Other trials of Collection of data from the patient's medical file

Trials testing the same drug.

Other Assistance Publique - Hôpitaux de Paris trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06365268.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing