NCT06356662 is a Phase 1 clinical trial of Tenofovir Disoproxil Fumarate in Parkinson Disease, sponsored by The Fourth Affiliated Hospital of Zhejiang University School of Medicine.

Who is sponsoring NCT06356662?

NCT06356662 is sponsored by The Fourth Affiliated Hospital of Zhejiang University School of Medicine.

What drugs are being tested in NCT06356662?

Interventions in NCT06356662: Tenofovir Disoproxil Fumarate.

What condition does NCT06356662 study?

NCT06356662 studies Parkinson Disease.

Is NCT06356662 still recruiting?

NCT06356662 is currently recruiting now. Last updated 17 February 2025.

Last reviewed 2025-02-17 · How we verify

NCT06356662

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Tenofovir Disoproxil Fumarate in the Treatment of Parkinson's Disease

Recruiting now Phase 1 Last updated 17 February 2025

What this trial tests

Phase 1 trial testing Tenofovir Disoproxil Fumarate in Parkinson Disease in 60 participants. Currently enrolling.

Timeline

23 January 2024

Primary endpoint
31 December 2025

31 December 2025

Quick facts

Lead sponsor	The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Phase	Phase 1
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	60
Start date	23 January 2024
Primary completion	31 December 2025
Estimated completion	31 December 2025
Sites	1 location across China

Drugs / interventions tested

Tenofovir Disoproxil Fumarate — full drug profile →

Conditions studied

Parkinson Disease — all drugs for Parkinson Disease →

Sponsor

The Fourth Affiliated Hospital of Zhejiang University School of Medicine

Who can join

Adults 18 to 65, any sex, with Parkinson Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To evaluate the efficacy and safety of tenofovir disoproxil fumarate in the treatment of Parkinson's disease. The changes of motor symptoms and the occurrence of adverse reactions in early Parkinson's disease patients who took tenofovir disoproxil fumarate and did not take Tenofovir disoproxil fumarate at different time points were compared.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Underestimated virus impaired cognition-more evidence and more work to do.
Awan MUN, Mahmood F, Peng XB, Zheng F, et al · · 2025 · cited 1× · PMID 40421014 · DOI 10.3389/fimmu.2025.1550179

Verify or expand the search:

Other trials of Tenofovir Disoproxil Fumarate

Trials testing the same drug.

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Other recruiting trials for Parkinson Disease

Currently open trials in the same condition.

NCT07399496 — Accelerated TMS for Apathy in PD · NA · recruiting
NCT07371338 — Phase 1 Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of IPS101A in Parkinson's Disease Patients · Phase 1 · recruiting
NCT07442370 — The Effect of Functional Rotational Exercises on Fall Risk and Mobility in Parkinson's Disease Patients · NA · recruiting
NCT06848205 — Percept Transitions in FOG and PD · NA · recruiting
NCT07432958 — A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (P · Phase 2 · recruiting

Other The Fourth Affiliated Hospital of Zhejiang University School of Medicine trials

Trials by the same sponsor.

NCT07336888 — A Study on the Application of Positive Psychological Counseling Based on "Dou Bao" Software in Patients With Post-stroke · NA · not yet recruiting
NCT07375862 — Investigating the Clinical Benefits and Underlying Mechanisms of Danhong Injection in Modulating Mitochondrial Homeostas · Phase 2 · not yet recruiting
NCT07301437 — RWS of of Liraglutide Alone and in Combination With Orlistat for Weight Loss in Overweight/Obese Patients. · Phase 4 · not yet recruiting
NCT07289750 — The Effect of Alogliptin Combined With Actoplus Met on Glucose and Lipid Metabolism and Pancreatic Function in Patients · Phase 4 · not yet recruiting
NCT07512791 — Effect of Bagua Auriculotherapy on Pain in Patients Undergoing Hysteroscopy · NA · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06356662 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Last refreshed: 17 February 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06356662.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing