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NCT06586983
Decentralization of Hepatitis B Care in Sub-Saharan Africa: a Pilot Program in Ethiopia
trial testing Tenofovir Disoproxil Fumarate in Hepatitis B in 4,500 participants. Currently enrolling.
5 September 2028
Quick facts
| Lead sponsor | Oslo University Hospital |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 4,500 |
| Start date | 4 September 2024 |
| Primary completion | 5 September 2028 |
| Estimated completion | 5 September 2028 |
| Sites | 1 location across Ethiopia |
Drugs / interventions tested
- Tenofovir Disoproxil Fumarate — full drug profile →
Conditions studied
- Hepatitis B — all drugs for Hepatitis B →
Sponsor
Oslo University Hospital
Who can join
18 and older, any sex, with Hepatitis B. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this observational study is to study models of care for decentralized hepatitis B treatment in Ethiopia. Three different models of decentralized HBV care (standard model, simplified model, test-and-treat model) will be implemented at primary hospitals or health clinics in Ethiopia. Treatment will be given for free to patients who meet the treatment criteria. We will compare clinical outcome, laboratory outcomes and programmatic outcome measures between the 3 models.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Decentralization of hepatitis B care in sub-Saharan Africa: study protocol for a prospective cohort assessing three models of care in rural Ethiopia.
Malme KB, Berhe N, Hunduma F, Desalegn H, et al · · 2025 · PMID 41029661 · DOI 10.1186/s12913-025-13340-1
Verify or expand the search:
- PubMed search for NCT06586983
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Other Oslo University Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06586983 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Oslo University Hospital
- Last refreshed: 19 September 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06586983.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing