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NCT06340594
Single-stage ERCP and Laparoscopic Cholecystectomy for Cholecystocholedocholithiasis: Which to Start With?
trial testing Laproscopic cholecystectomy (LC) in Choledocholithiasis With Cholecystitis in 115 participants. Completed in 30 January 2024.
1 December 2023
Quick facts
| Lead sponsor | Assiut University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 115 |
| Start date | 1 January 2021 |
| Primary completion | 1 December 2023 |
| Estimated completion | 30 January 2024 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Laproscopic cholecystectomy (LC)
- Endoscopic Retrograde Cholangiopancreatography (ERCP)
Conditions studied
- Choledocholithiasis With Cholecystitis — all drugs for Choledocholithiasis With Cholecystitis →
- Biliary Stones — all drugs for Biliary Stones →
Sponsor
Assiut University
Who can join
Adults 18 to 80, any sex, with Choledocholithiasis With Cholecystitis or Biliary Stones. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Chronic calculous cholecystitis is associated with common bile duct (CBD) stones in approximately 12% of patients. These patients need both cholecystectomy and CBD clearance of stones. The standard for cholecystectomy is laparoscopic cholecystectomy (LC) and the mostly common treatment used for CBD clearance is Endoscopic Retrograde Cholangiopancreatography (ERCP). The two interventions can be combined to be done at the same time under single anesthesia session. Studies of single stage ERCP+LC showed confirmed the safety and efficacy of the combined technique. However, some surgeons start with the ERCP while others start with LC.The aim of this study is to compare the start with ERCP followed by LC to the start with LC followed by ERCP when the two techniques are combined at the same session for treatment of chronic calculous cholecystitis associated with CBD stones regarding efficacy and safety of the two approaches.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Single-stage laparoendoscopic management of cholecystocholedocholithiasis: A retrospective study comparing starting with ERCP versus with laparoscopic cholecystectomy.
Sayed MM, Abdelmohsen AS, Ibrahim M, Raafat M. · · 2025 · cited 2× · PMID 39710368 · DOI 10.14701/ahbps.24-157
Verify or expand the search:
- PubMed search for NCT06340594
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Choledocholithiasis With Cholecystitis
Currently open trials in the same condition.
- NCT07503964 — The Significance of Laparoscopic Transcystic Papilla Vateri Balloon Dilatation in Patients With Choledocholithiasis. · NA · active not recruiting
Other Assiut University trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06340594 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assiut University
- Last refreshed: 2 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06340594.
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